Mixed systems based on the cationic surfactant with a butyl carbamate fragment and nonionic surfactant Tween 80: Aggregation behavior and solubilization properties

被引：7

作者：

Mirgorodskaya, A. B. ^{[1
]}

Kushnazarova, R. A. ^{[1
]}

Shcherbakov, A. Yu. ^{[1
]}

Lukashenko, S. S. ^{[1
]}

Zhukova, N. A. ^{[1
]}

Mamedov, V. A. ^{[1
,2
]}

Zakharova, L. Ya. ^{[1
,2
]}

Sinyashin, O. G. ^{[2
]}

机构：

[1] Russian Acad Sci, Kazan Sci Ctr, Subdivis Fed Res Ctr, AE Arbuzov Inst Organ & Phys Chem, 8 Ul Akad Arbuzova, Kazan 420088, Russia

[2] Kazan Natl Res Technol Univ, 68 Ul K Marksa, Kazan 420015, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2018年 / 67卷 / 11期

基金：

俄罗斯科学基金会;

关键词：

surfactants; aggregation; mixed micelles; solubilization; drugs; INDOMETHACIN; DRUGS;

D O I：

10.1007/s11172-018-2319-9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mixed micelles are formed in the binary compositions based on the cationic surfactant functionalized by the butyl carbamate fragment and nonionic surfactant Tween 80 in aqueous solutions. The aggregation parameters of the formed micelles (critical micelle concentration, size, and surface potential) depend on the component ratio in the system. The solubilization effect of individual and mixed micelles on the drugs of the heterocyclic series, indomethacin and 1-[5-(4-chlorophenyl)-3-phenylpyrrol-2-yl)]benzimidazol-2(3H)-one, was quantitatively characterized.

引用

页码：1992 / 1996

页数：5

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