Survival of an islet β-cell in type 2 diabetes Curbing the effects of amyloid cytotoxicity

被引：8
|
作者：
Loomes, Kerry M. [1 ,2 ]
机构：
[1] Univ Auckland, Sch Biol Sci, Inst Innovat Biotechnol, Auckland 1, New Zealand
[2] Univ Auckland, Maurice Wilkins Ctr Mol Biodiscovery, Auckland 1, New Zealand
来源：
ISLETS | 2011年 / 3卷 / 01期
关键词：
amylin; islet amyloid; chaperone; beta-cell; islet amyloid polypeptide; type 2 diabetes mellitus; HUMAN AMYLIN; POLYPEPTIDE; APOPTOSIS; OLIGOMERS; SECRETION; ACTIVATION; PROTEINS; PEPTIDE; INSULIN; BIOLOGY;
D O I：
10.4161/isl.3.1.14258
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：38 / 39
页数：2
相关论文
共 50 条
  • [1] Islet amyloid and type 2 diabetes mellitus
    Höppener, JWM
    Ahrén, B
    Lips, CJM
    NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (06): : 411 - 419
  • [2] ISLET AMYLOID AND TYPE-2 DIABETES
    CLARK, A
    DIABETIC MEDICINE, 1989, 6 (07) : 561 - 567
  • [3] The implication for islet amyloid in type 2 diabetes
    Westermark, G. T.
    FEBS JOURNAL, 2008, 275 : 27 - 27
  • [4] Islet amyloid polypeptide and type 2 diabetes
    Marzban, L
    Park, K
    Verchere, CB
    EXPERIMENTAL GERONTOLOGY, 2003, 38 (04) : 347 - 351
  • [5] Role of islet amyloid in type 2 diabetes mellitus
    Höppener, JWM
    Lips, CJM
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2006, 38 (5-6): : 726 - 736
  • [6] ISLET AMYLOID - AN ENIGMA OF TYPE-2 DIABETES
    CLARK, A
    DIABETES-METABOLISM REVIEWS, 1992, 8 (02): : 117 - 132
  • [7] Glycated Insulin Exacerbates the Cytotoxicity of Human Islet Amyloid Polypeptides: a Vicious Cycle in Type 2 Diabetes
    Ma, Liang
    Yang, Chen
    Huang, Lianqi
    Chen, Yuchen
    Li, Yang
    Cheng, Cheng
    Cheng, Biao
    Zheng, Ling
    Huang, Kun
    ACS CHEMICAL BIOLOGY, 2019, 14 (03) : 486 - 496
  • [8] β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition
    Jurgens, Catherine A.
    Toukatly, Mirna N.
    Fligner, Corinne L.
    Udayasankar, Jayalakshmi
    Subramanian, Shoba L.
    Zraika, Sakeneh
    Aston-Mourney, Kathryn
    Carr, Darcy B.
    Westermark, Per
    Westermark, Gunilla T.
    Kahn, Steven E.
    Hull, Rebecca L.
    AMERICAN JOURNAL OF PATHOLOGY, 2011, 178 (06): : 2632 - 2640
  • [9] Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes?
    A. Clark
    M. R. Nilsson
    Diabetologia, 2004, 47 : 157 - 169
  • [10] Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology
    Jaikaran, ETAS
    Clark, A
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2001, 1537 (03): : 179 - 203
12345