Facile synthesis of water soluble silver ferrite (AgFeO2) nanoparticles and their biological application as antibacterial agents

被引:77
作者
Abdelhamid, Hani Nasser [1 ,2 ]
Talib, Abou [3 ]
Wu, Hui-Fen [1 ,3 ,4 ,5 ,6 ,7 ]
机构
[1] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 804, Taiwan
[2] Assiut Univ, Dept Chem, Assiut 71515, Egypt
[3] Kaohsiung Med Univ, Coll Pharm, Sch Pharm, Kaohsiung 807, Taiwan
[4] Natl Sun Yat Sen Univ, Ctr Nanosci & Nanotechnol, Kaohsiung 804, Taiwan
[5] Natl Sun Yat Sen Univ, Doctoral Degree Program Marine Biotechnol, Kaohsiung 80424, Taiwan
[6] Acad Sinica, Kaohsiung 80424, Taiwan
[7] Natl Sun Yat Sen Univ, Inst Med Sci & Technol, Kaohsiung 804, Taiwan
关键词
SOL-GEL METHOD; GRAPHENE OXIDE; BIOMEDICAL APPLICATIONS; MAGNETIC NANOPARTICLES; ANTIMICROBIAL MATERIAL; PATHOGENIC BACTERIA; ESCHERICHIA-COLI; AG NANOPARTICLES; IRON-OXIDE; NANOCOMPOSITES;
D O I
10.1039/c4ra14461a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The syntheses and antibacterial activity of AgFeO2 and AgFO2 modified polyethylene glycols (PEGs) are reported. The antibacterial activity is investigated against different pathogenic bacteria for possible water treatment applications. The antibacterial activities are quantified by counting the colonies formed in a petri dish, a method called plate counting, and by measuring the turbidity using optical density at wavelength 600 nm (OD600). AgFeO2 nanoparticles (NPs) offer high antibacterial efficiency and can be easily separated from the solution using a small magnetic bar. The data revealed that higher concentrations led to high potency. PEG not only improves the biocompatibility of AgFeO2 by mitigating the cytotoxicity of the core but also improves the dispersion of the AgFeO2 NPs. Because of their superior cytotoxicity and magnetic property, this antibacterial material may have great potential in biomedical applications in the near future.
引用
收藏
页码:34594 / 34602
页数:9
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