Novel biomarkers in human terminal heart failure and under mechanical circulatory support

被引:18
作者
Kramer, Frank [1 ]
Milting, Hendrik [2 ]
机构
[1] Bayer HealthCare, Global Biomarker Res, Pharma Res Ctr Wuppertal, D-42096 Wuppertal, Germany
[2] Ruhr Univ Bochum, Univ Klinikum, Herz & Diabet Zentrum NRW, Klin Thorax & Kardiovaskularchirurg,Erich & Hann, Bochum, Germany
关键词
Cardiovascular disease; heart failure; heart transplantation; ventricular assist device; bridge to transplantation; mechanical circulatory support; VENTRICULAR ASSIST DEVICE; GROWTH-DIFFERENTIATION FACTOR-15; BRAIN NATRIURETIC PEPTIDE; TGF-BETA SUPERFAMILY; ACUTE MYOCARDIAL-INFARCTION; MATRIX METALLOPROTEINASES; TISSUE INHIBITOR; GROWTH/DIFFERENTIATION FACTOR-5; SOLUBLE ST2; OSTEOGENIC DIFFERENTIATION;
D O I
10.3109/1354750X.2011.561498
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
This review summarizes recent findings on novel biochemical plasma biomarkers in terminal heart failure patients, which might predict an advanced mortality risk or even recovery. Moreover, we discussed the regulation of these heart failure-related biomarkers under mechanical circulatory support.
引用
收藏
页码:S31 / S41
页数:11
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