A Highly Sensitive Nonenzymatic Glucose Biosensor Based on the Regulatory Effect of Glucose on Electrochemical Behaviors of Colloidal Silver Nanoparticles on MoS2

被引：49

作者：

Anderson, Kash ^{[1
]}

Poulter, Benjamin ^{[1
]}

Dudgeon, John ^{[2
]}

Li, Shu-En ^{[1
]}

Ma, Xiang ^{[1
,3
]}

机构：

[1] Idaho State Univ, Dept Chem, Pocatello, ID 83201 USA

[2] Idaho State Univ, Dept Anthropol, Pocatello, ID 83201 USA

[3] Grand View Univ, Dept Chem, Des Moines, IA 50316 USA

来源：

SENSORS | 2017年 / 17卷 / 08期

关键词：

glucose biosensor; nonenzymatic; colloidal silver nanoparticle; molybdenum disulfide; DIRECT ELECTRON-TRANSFER; BLOOD-GLUCOSE; IN-VITRO; OXIDASE; NANOSHEETS; FILM; POLYMERIZATION; IMMOBILIZATION; NANOWIRES; CHEMISTRY;

D O I：

10.3390/s17081807

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel and highly sensitive nonenzymatic glucose biosensor was developed by nucleating colloidal silver nanoparticles (AgNPs) on MoS2. The facile fabrication method, high reproducibility (97.5%) and stability indicates a promising capability for large-scale manufacturing. Additionally, the excellent sensitivity (9044.6 mu A.mM(-1).cm(2)), low detection limit (0.03 mu M), appropriate linear range of 0.1-1000 mu M, and high selectivity suggests that this biosensor has a great potential to be applied for noninvasive glucose detection in human body fluids, such as sweat and saliva.

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