Clinical application of platelet-rich plasma for the treatment of refractory sinus wounds.

Objective: To evaluate the clinical efficacy of Platelet-Rich Plasma (PRP) in the treatment of refractory sinus wounds. Methods: Twelve patients with refractory sinus wounds were recruited for this study. Among them, the sinus wounds in eight patients were caused by fracture fixation and in four patients were caused by trauma. The PRP was locally injected following wound debridement. The strength of pain and wound healing were observed after treatment. Results: In the 12 cases that were treated with PRP, 7 cases exhibited significant pain relief, 6 cases were partly healed and 6 cases were completed healed. Conclusions: The local injection of PRP which is simple and safe has shown significant healing efficiency and pain relief in the treatment of refractory sinus wounds.