CONTROL OF CONFORMATIONAL STRUCTURES OF POLYACRYLAMIDE MACROMOLECULES

The purpose of the study is to propose a variant of the polyacrylamide modification mechanism with the use of serine. Methods: determination of the molecular weight of polyacrylamide macromolecules was calculated using the Mark-Houwink equation. Results: The paper presents the results of the study on the development of accessible ways to control the conformational structures of high-molecular compounds on the example of polyacrylamide. The authors propose a technological and affordable method for fixing and preserving conformational structures of macromolecules based on modification processes with the use of low-molecular compounds containing two active functional groups (chlorohydrins, glycols, or amino acids). Modification schemes and basic physicochemical properties of modified structures are presented. Based on the analytical review and results of the study, it was found that the processes of controlling the conformational structures of high-molecular compound macromolecules had not been sufficiently studied. It was established that the main available, technologically simple, but insufficiently effective method of carrying out conformational changes in polyacrylamide macromolecules was the process of its hydration.