Diterpenoids from Azorella madreporica and Their Antibacterial Activity

被引：14

作者：

Areche, Carlos ^{[1
]}

Vaca, Inmaculada ^{[1
]}

Loyola, Luis A. ^{[2
]}

Borquez, Jorge ^{[2
]}

Rovirosa, Juana ^{[1
]}

San-Martin, Aurelio ^{[1
]}

机构：

[1] Univ Chile, Fac Sci, Dept Chem, Santiago 8320000, Chile

[2] Univ Antofagasta, Fac Basic Sci, Dept Chem, Antofagasta, Chile

来源：

PLANTA MEDICA | 2010年 / 76卷 / 15期

关键词：

Azorella madreporica; Apiaceae; diterpenoids; mulinane; antibacterial activity; COMPACTA; ACID;

D O I：

10.1055/s-0030-1249835

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new diterpenoids, mulin-12-en-16-al-20-oic acid and 13-alpha-hydroxy-mulin-11-en-14-one-20-oic acid, were isolated from Azorella madreporica. Their structures were identified on the basis of one-dimensional and two-dimensional NMR experiments. Their antibacterial activity was also tested.

引用

页码：1749 / 1751

页数：3

共 9 条

[1] Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus [J].

Areche, Cados ;

Loyola, Luis A. ;

Borquez, Jorge ;

Rovirosa, Juana ;

San-Martin, Aurelio .

MAGNETIC RESONANCE IN CHEMISTRY, 2008, 46 (08) :765-768

[2] Mulinane-type diterpenoids from Mulinum spinosum [J].

Chlaramello, AI ;

Ardanaz, CE ;

García, EE ;

Rossomando, PC .

PHYTOCHEMISTRY, 2003, 63 (08) :883-886

[3]

Jorgensen J.H., 1999, Manual of Clinical Microbiology, 7th ed Murray, P.R., Baron, E.J., Pfaller, M.A., Tenover, F.C., Yolken, R.H., P1526

[4] Yaretol, a norditerpenoid from Azorella madreporica [J].

Loyola, LA ;

Bórquez, J ;

Morales, G ;

San-Martín, A ;

Manríquez, V ;

Boys, D ;

Darias, J .

JOURNAL OF NATURAL PRODUCTS, 2002, 65 (11) :1678-1680

[5] Madreporanone, a unique diterpene with a novel skeleton from Azorella madreporica [J].

Loyola, LA ;

Bórquez, J ;

Morales, G ;

San-Martín, A ;

Darias, J .

TETRAHEDRON LETTERS, 2002, 43 (36) :6359-6362

[6] Diterpenoids from Azorella compacta [J].

Loyola, LA ;

Borquez, J ;

Morales, G ;

Martin, AS .

PHYTOCHEMISTRY, 1997, 44 (04) :649-651

[7] Mulinolic acid, a diterpenoid from Mulinum crassifolium [J].

Loyola, LA ;

Borquez, J ;

Morales, G ;

SanMartin, A .

PHYTOCHEMISTRY, 1996, 43 (01) :165-168

[8] A new antitubercular mulinane diterpenoid from Azorella madreporica Clos [J].

Wächter, GA ;

Franzblau, SG ;

Montenegro, G ;

Suarez, E ;

Fortunato, RH ;

Saavedra, E ;

Timmermann, BN .

JOURNAL OF NATURAL PRODUCTS, 1998, 61 (07) :965-968

[9] Antibacterial diterpenoid acids from Azorella compacta [J].

Wächter, GA ;

Matooq, G ;

Hoffmann, JJ ;

Maiese, WM ;

Singh, MP ;

Montenegro, G ;

Timmermann, BN .

JOURNAL OF NATURAL PRODUCTS, 1999, 62 (09) :1319-1321

← 1 →