Intrathecal Trastuzumab Halts Progression of CNS Metastases in Breast Cancer

被引：32

作者：

Bousquet, Guilhem ^{[1
,2
,3
]}

Darrouzain, Francois ^{[4
,5
,6
]}

de Bazelaire, Cedric ^{[1
,2
,3
]}

Ternant, David ^{[4
,5
,6
]}

Barranger, Emmanuel ^{[1
,7
]}

Winterman, Sabine ^{[8
]}

Madelaine-Chambin, Isabelle ^{[7
]}

Thiebaut, Jean-Baptiste ^{[9
]}

Polivka, Marc ^{[3
]}

Paintaud, Gilles ^{[4
,5
,6
]}

Culine, Stephane ^{[1
,3
]}

Janin, Anne ^{[1
,2
,3
]}

机构：

[1] Univ Paris Diderot, UMR S728, Paris, France

[2] INSERM, U728, Paris, France

[3] Hop St Louis, AP HP, Paris, France

[4] Univ Tours, Tours, France

[5] CNRS, UMR 7292, Tours, France

[6] CHR Univ Tours, Tours, France

[7] Hop Lariboisiere, AP HP, F-75475 Paris, France

[8] Hop Avicenne, AP HP, Paris, France

[9] Fdn Ophtalmol Rothschild, Paris, France

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2016年 / 34卷 / 16期

关键词：

BLOOD-BRAIN-BARRIER; PHARMACOKINETIC ANALYSIS; MACULAR DEGENERATION; MONOCLONAL-ANTIBODY; PIGLET MODEL; AGE; 4TH-VENTRICLE; SAFETY;

D O I：

10.1200/JCO.2012.44.8894

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：E151 / E155

页数：5

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