Differentiation of mucous cells and regulation of the gelling mucin Muc5b: a new tool for ex vivo studies and preclinical studies in vivo

被引:1
作者
Desseyn, Jean-Luc [1 ]
Portal, Celine [1 ]
Gottrand, Frederic [1 ]
Gouyer, Valerie [1 ]
机构
[1] Univ Lille, INSERM, UMR 995, LIRIC,CHU Lille, Lille, France
来源
M S-MEDECINE SCIENCES | 2017年 / 33卷 / 05期
关键词
MUCUS;
D O I
10.1051/medsci/20173305006
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:478 / 480
页数:3
相关论文
共 8 条
[1]   Biological modeling of mucus to modulate mucus barriers [J].
Desseyn, Jean-Luc ;
Gouyer, Valerie ;
Gottrand, Frederic .
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2016, 310 (04) :G225-G227
[2]   Custom modification in vivo of mucus properties Proof of concept and potential applications [J].
Desseyn, Jean-Luc ;
Gouyer, Valerie ;
Gottrand, Frederic .
M S-MEDECINE SCIENCES, 2015, 31 (12) :1063-1066
[3]   The Extraordinarily Complex but Highly Structured Organization of Intestinal Mucus-Gel Unveiled in Multicolor Images [J].
Gouyer, Valerie ;
Gottrand, Frederic ;
Desseyn, Jean-Luc .
PLOS ONE, 2011, 6 (04)
[4]   Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments [J].
Portal, Celine ;
Gouyer, Valerie ;
Gottrand, Frederic ;
Desseyn, Jean-Luc .
PLOS ONE, 2017, 12 (03)
[5]   In vivo imaging of the Muc5b gel-forming mucin [J].
Portal, Celine ;
Gouyer, Valerie ;
Magnien, Mylene ;
Plet, Segolene ;
Gottrand, Frederic ;
Desseyn, Jean-Luc .
SCIENTIFIC REPORTS, 2017, 7
[6]   Confocal endomicroscopy of the lung: From the bronchus to the alveolus [J].
Salauen, M. ;
Bourg-Heckly, G. ;
Thiberville, L. .
REVUE DES MALADIES RESPIRATOIRES, 2010, 27 (06) :579-588
[7]   MUC5B Leads to Aggressive Behavior of Breast Cancer MCF7 Cells [J].
Valque, Helene ;
Gouyer, Valerie ;
Gottrand, Frederic ;
Desseyn, Jean-Luc .
PLOS ONE, 2012, 7 (10)
[8]   Abnormal expression of Muc5b in Cftr-null mice and in mammary tumors of MMTV-ras mice [J].
Valque, Helene ;
Gouyer, Valerie ;
Husson, Marie-Odile ;
Gottrand, Frederic ;
Desseyn, Jean-Luc .
HISTOCHEMISTRY AND CELL BIOLOGY, 2011, 136 (06) :699-708