Ceria/vinylpyridine polymer nanocomposite:: an ecofriendly catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones

被引：41

作者：

Sabitha, G ^{[1
]}

Reddy, KB

Yadav, JS

Shailaja, D

Sivudu, KS

机构：

[1] Indian Inst Chem Technol, Organ Div 1, Hyderabad 500007, Andhra Pradesh, India

[2] Indian Inst Chem Technol, Organ Coatings & Polymers Div, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 47期

关键词：

Biginelli reaction; water; heterogeneous catalysis; ceria nanoparticles; reusability;

D O I：

10.1016/j.tetlet.2005.09.100

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The three-component condensation of aldehydes, beta-ketoesters and urea has been carried out in water using ceria (cerium oxide, CeO2) nanoparticles supported on poly(4vp-co-dvb) as a catalyst for the preparation of 3,4-dihydropyrimidin-2(1H)-ones in good yields. The catalyst was recovered easily and reused without loss of its activity. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：8221 / 8224

页数：4

共 20 条

[11] Lanthanide triflate catalyzed Biginelli reaction. One-pot synthesis of dihydropyrimidinones under solvent-free conditions [J].

Ma, Y ;

Qian, CT ;

Wang, LM ;

Yang, M .

JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (12) :3864-3868

[12]

Nagarathnam D., 1997, PCT Int. Appl., Patent No. [9717969, WO 97 17, 969]

[13] Indium(III) chloride-catalyzed one-pot synthesis of dihydropyrimidinones by a three-component coupling of 1,3-dicarbonyl compounds, aldehydes, and urea: An improved procedure for the Biginelli reaction [J].

Ranu, BC ;

Hajra, A ;

Jana, U .

JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (19) :6270-6272

[14] Zirconium(IV) chloride catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones [J].

Reddy, CV ;

Mahesh, M ;

Raju, PVK ;

Babu, TR ;

Reddy, VVN .

TETRAHEDRON LETTERS, 2002, 43 (14) :2657-2659

[15] CALCIUM-ENTRY BLOCKERS AND ACTIVATORS - CONFORMATIONAL AND STRUCTURAL DETERMINANTS OF DIHYDROPYRIMIDINE CALCIUM-CHANNEL MODULATORS [J].

ROVNYAK, GC ;

KIMBALL, SD ;

BEYER, B ;

CUCINOTTA, G ;

DIMARCO, JD ;

GOUGOUTAS, J ;

HEDBERG, A ;

MALLEY, M ;

MCCARTHY, JP ;

ZHANG, RA ;

MORELAND, S .

JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (01) :119-129

[16] Vanadium(III) chloride catalyzed Biginelli condensation:: solution phase library generation of dihydropyrimidin-(2H)-ones [J].

Sabitha, G ;

Reddy, GSKK ;

Reddy, KB ;

Yadav, JS .

TETRAHEDRON LETTERS, 2003, 44 (34) :6497-6499

[17] Silica sulfuric acid:: an efficient and reusable catalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones [J].

Salehi, P ;

Dabiri, M ;

Zolfigol, MA ;

Fard, MAB .

TETRAHEDRON LETTERS, 2003, 44 (14) :2889-2891

[18]

SIDLER DR, 1999, Patent No. 9907695

[19]

SIVUDU KS, UNPUB MACROMOL RAPID

[20] One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using boric acid as catalyst [J].

Tu, S ;

Fang, F ;

Miao, CB ;

Jiang, H ;

Feng, YJ ;

Shi, DQ ;

Wang, XS .

TETRAHEDRON LETTERS, 2003, 44 (32) :6153-6155

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