Prevalence of fecal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae among healthy adult people in Japan

被引：55

作者：

Luvsansharav, Ulzii-Orshikh ^{[1
]}

Hirai, Itaru ^{[1
]}

Niki, Marie ^{[1
]}

Nakata, Arisa ^{[1
]}

Yoshinaga, Aya ^{[1
]}

Moriyama, Toshiki ^{[2
]}

Yamamoto, Yoshimasa ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Med, Dept Bioinformat, Suita, Osaka 5650871, Japan

[2] Osaka Univ, Hlth Care Ctr, Osaka 5600043, Japan

来源：

JOURNAL OF INFECTION AND CHEMOTHERAPY | 2011年 / 17卷 / 05期

关键词：

Enterobacteriaceae; Extended-spectrum beta-lactamase (ESBL); Japanese; ESCHERICHIA-COLI; INDIVIDUALS; SPREAD; GENES; ASIA;

D O I：

10.1007/s10156-011-0225-2

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In Japan, the prevalence of extended-spectrum beta-lactamase (ESBL) producers in hospital settings has shown an increasing trend. In the present study, we investigated the prevalence of the fecal carriage of ESBL-producing Enterobacteriaceae among healthy adults. Stool samples were collected for the phenotypic and genotypic identification of ESBL-producing Enterobacteriaceae. We found the prevalence of ESBL producers to be 6.4% by phenotypic identification, and 92.9% of them possessed the bla(CTX-M) gene. Among the CTX-M ESBL-producing Enterobacteriaceae, we identified 11 Escherichia coli and 2 Klebsiella pneumonia strains. The findings suggest that the fecal carriage of CTX-M-type ESBL producers by healthy people is rapidly increasing in Japan. This may be one of the causes of the increased spread of ESBL-producing bacteria in hospitals.

引用

页码：722 / 725

页数：4

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