Advance of the application of nano-controlled release system in ophthalmic drug delivery

被引：66

作者：

Wang, Xuanzhong ^{[1
]}

Wang, Shurong ^{[1
]}

Zhang, Yan ^{[1
]}

机构：

[1] Jilin Univ, Teaching Hosp 2, Dept Ophthalmol, 218 Ziqiang St, Changchun 130041, Peoples R China

来源：

DRUG DELIVERY | 2016年 / 23卷 / 08期

关键词：

Drug controlled release system; drug therapy; eyes; nanometer materials; PLGA NANOPARTICLES; CHOROIDAL NEOVASCULARIZATION; INTRAVITREAL INJECTION; NANOSUSPENSIONS; FORMULATION; MOVEMENT; RETINA; DESIGN; EYE;

D O I：

10.3109/10717544.2015.1116025

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The ocular prescription application of nanometer materials are mainly concentrated in controlled release systems. Due to the unique properties of nanometer materials such as higher bioavailability and less side effects, it has great advantages in carrying ocular drugs of eye diseases compared with the traditional dosing method. As a result, nano-controlled release system has good application prospect in eye diseases. At present, a variety of different types of nano-controlled release systems have been used to enhance the efficiency of the ocular drugs including nanomicelles, nanoparticles, nanosuspensions, liposomes and dendrimers. In this article, the research progress and the application of nano-controlled release system in ophthalmic drug delivery are reviewed.

引用

页码：2897 / 2901

页数：5

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