Nosocomial Infections and Role of Nanotechnology

被引：29

作者：

Ananda, Thripthi ^{[1
]}

Modi, Ankita ^{[2
]}

Chakraborty, Ishita ^{[3
]}

Managuli, Vishwanath ^{[4
]}

Mukhopadhyay, Chiranjay ^{[1
,5
]}

Mazumder, Nirmal ^{[3
]}

机构：

[1] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Microbiol, Manipal 576104, Karnataka, India

[2] Indian Inst Technol Madras, Dept Appl Mech, Chennai 600036, Tamil Nadu, India

[3] Manipal Acad Higher Educ, Manipal Sch Life Sci, Dept Biophys, Manipal 576104, Karnataka, India

[4] Manipal Acad Higher Educ, Manipal Inst Technol, Dept Mech & Mfg Engn, Manipal 576104, Karnataka, India

[5] Manipal Acad Higher Educ, Ctr Emerging & Trop Dis, Manipal 576104, Karnataka, India

来源：

BIOENGINEERING-BASEL | 2022年 / 9卷 / 02期

关键词：

Healthcare; Hospital-acquired infection; Mul-tidrug resistance; Nanotechnology; Nosocomial infection;

D O I：

10.3390/bioengineering9020051

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Nosocomial infections, termed hospital-acquired infections (HAIs), are acquired from a healthcare or hospital setting. HAI is mainly caused by bacteria, such as Acinetobacter baumannii, Klebsiella pneumoniae, Escherichia coli, Enterococci spp., Methicillin-resistant Staphylococcus aureus (MRSA), and many more. Due to growing antibacterial resistance, nanotechnology has paved the way for more potent and sensitive methods of detecting and treating bacterial infections. Nanoparticles have been used with molecular beacons for identifying bactericidal activities, targeting drug delivery, and anti-fouling coatings, etc. This review addresses the looming threat of nosocomial infections, with a focus on the Indian scenario, and major initiatives taken by medical bodies and hospitals in spreading awareness and training. Further, this review focuses on the potential role nanotechnology can play in combating the spread of these infections.

引用

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