Quantitative detection of adenosine in urine using silver enhancement of aptamer-gold nanoparticle aggregation and progressive dilution

被引：23

作者：

Liu, Zhao Fang

Ge, Jing

Zhao, Xin Sheng ^{[1
]}

机构：

[1] Peking Univ, Beijing Natl Lab Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Dept Chem Biol,Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 17期

关键词：

DNA APTAMER; NANO-FLARES; BIOSENSOR; APTASENSOR; CELLS;

D O I：

10.1039/c1cc10460h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We implement the progressive dilution strategy to bring assays based on gold nanoparticles to a quantitative level. This is demonstrated by the detection of adenosine in urine by combining progressive dilution with the silver enhancement of aptamer-gold nanoparticle aggregation, giving good accuracy, high selectivity, and an unlimited dynamic range above LOD.

引用

页码：4956 / 4958

页数：3

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