Adherence to Mediterranean diet in Crohn's disease

被引:55
作者
Papada, Efstathia [1 ]
Amerikanou, Charalampia [1 ]
Forbes, Alastair [2 ]
Kaliora, Andriana C. [1 ]
机构
[1] Harokopio Univ, Sch Hlth Sci & Educ, Dept Dietet & Nutr Sci, 70 El Venizelou Ave, Athens 17671, Greece
[2] Univ East Anglia, Norwich Med Sch, Bob Champ Bldg,James Watson Rd, Norwich NR4 7UQ, Norfolk, England
关键词
Mediterranean diet; Crohn's disease; Quality of life; Disease activity; Inflammation; QUALITY-OF-LIFE; INFLAMMATORY-BOWEL-DISEASE; NUTRITION;
D O I
10.1007/s00394-019-01972-z
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Purpose To assess the adherence to MD in patients with Crohn's disease (CD). Methods Outpatients with CD were enrolled in this protocol. Medical history, disease activity, dietary intake, habitual Mediterranean diet (MedDiet) score, anthropometric measurements and Inflammatory Bowel Disease Questionnaire (IBDQ) were recorded. Blood samples were collected for quantification of biochemical and inflammatory indices. Results A total of 86 patients with CD were enrolled: 41 in relapse (5 <= Harvey Bradshaw Index <= 14) and 45 in remission (Harvey Bradshaw Index <= 4). Adherence to MD was greater in patients with inactive disease. The MedDiet score correlated positively with the IBDQ (p = 0.008) and negatively with disease activity (p < 0.001). Conclusions Adherence to Mediterranean diet is associated with improved quality of life in CD patients. Higher adherence to Mediterranean diet could be of importance in patients with CD to improve quality of life and reduce disease activity.
引用
收藏
页码:1115 / 1121
页数:7
相关论文
共 21 条
[1]   Relationship of the adherence to the Mediterranean diet with health-related quality of life and treatment satisfaction in patients with type 2 diabetes mellitus: a post-hoc analysis of a cross-sectional study [J].
Alcubierre, Nuria ;
Martinez-Alonso, Montserrat ;
Valls, Joan ;
Rubinat, Esther ;
Traveset, Alicia ;
Hernandez, Marta ;
Dolores Martinez-Gonzalez, Maria ;
Granado-Casas, Minerva ;
Jurjo, Carmen ;
Vioque, Jesus ;
Maria Navarrete-Munoz, Eva ;
Mauricio, Didac .
HEALTH AND QUALITY OF LIFE OUTCOMES, 2016, 14
[2]   Systematic Review of Health-related Quality of Life Measures for Inflammatory Bowel Disease [J].
Alrubaiy, Laith ;
Rikaby, Ibtihal ;
Dodds, Phedra ;
Hutchings, Hayley Anne ;
Williams, John Gordon .
JOURNAL OF CROHNS & COLITIS, 2015, 9 (03) :284-292
[3]   AGA Clinical Practice Update on Functional Gastrointestinal Symptoms in Patients With Inflammatory Bowel Disease: Expert Review [J].
Colombel, Jean-Frederic ;
Shin, Andrea ;
Gibson, Peter R. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2019, 17 (03) :380-+
[4]   High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome [J].
De Filippis, Francesca ;
Pellegrini, Nicoletta ;
Vannini, Lucia ;
Jeffery, Ian B. ;
La Storia, Antonietta ;
Laghi, Luca ;
Serrazanetti, Diana I. ;
Di Cagno, Raffaella ;
Ferrocino, Ilario ;
Lazzi, Camilla ;
Turroni, Silvia ;
Cocolin, Luca ;
Brigidi, Patrizia ;
Neviani, Erasmo ;
Gobbetti, Marco ;
O'Toole, Paul W. ;
Ercolini, Danilo .
GUT, 2016, 65 (11) :1812-1821
[5]   Immunoregulatory Pathways Involved in Inflammatory Bowel Disease [J].
Fonseca-Camarillo, Gabriela ;
Yamamoto-Furusho, Jesus K. .
INFLAMMATORY BOWEL DISEASES, 2015, 21 (09) :2188-2193
[6]   ESPEN guideline: Clinical nutrition in inflammatory bowel disease [J].
Forbes, Alastair ;
Escher, Johanna ;
Hebuterne, Xavier ;
Klek, Stanislaw ;
Krznaric, Zeljko ;
Schneider, Stephane ;
Shamir, Raanan ;
Stardelova, Kalina ;
Wierdsma, Nicolette ;
Wiskin, Anthony E. ;
Bischoff, Stephan C. .
CLINICAL NUTRITION, 2017, 36 (02) :321-347
[7]   Role of nutrition and microbiota in susceptibility to inflammatory bowel diseases [J].
Gentschew, Liljana ;
Ferguson, Lynnette R. .
MOLECULAR NUTRITION & FOOD RESEARCH, 2012, 56 (04) :524-535
[8]   Use of the low-FODMAP diet in inflammatory bowel disease [J].
Gibson, Peter R. .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2017, 32 :40-42
[9]   A NEW MEASURE OF HEALTH-STATUS FOR CLINICAL-TRIALS IN INFLAMMATORY BOWEL-DISEASE [J].
GUYATT, G ;
MITCHELL, A ;
IRVINE, EJ ;
SINGER, J ;
WILLIAMS, N ;
GOODACRE, R ;
TOMPKINS, C .
GASTROENTEROLOGY, 1989, 96 (03) :804-810
[10]  
HARVEY RF, 1980, LANCET, V1, P514