Pd/C-catalyzed heterocyclization during copper-free Sonogashira coupling: synthesis of 2-benzylimidazo[1,2-a]pyrimidines in water

被引：17

作者：

Bakherad, Mohammad ^{[1
]}

Keivanloo, Ali ^{[1
]}

Kalantar, Zahra ^{[1
]}

Jajarmi, Saeideh ^{[1
]}

机构：

[1] Shahrood Univ Technol, Sch Chem, Shahrood, Iran

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 02期

关键词：

Pd/C-catalyzed; Sonogashira reaction; Aryl iodide; Imidazopyrimidine; ARYL BROMIDES; PALLADIUM; EFFICIENT; HALIDES; INHIBITORS; CHLORIDES; PHASE;

D O I：

10.1016/j.tetlet.2010.10.168

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of 2-benzylimidazo[1,2-a]pyrimidines in water is accomplished via Pd/C-catalyzed reaction of 2-imino-1-(2-propynyl)pyrimidine with various aryl iodides in the presence of K2CO3 as the base. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：228 / 230

页数：3

共 52 条

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