Psychiatric adverse events during levetiracetam therapy

被引：188

作者：

Mula, M ^{[1
]}

Trimble, MR ^{[1
]}

Yuen, A ^{[1
]}

Liu, RSN ^{[1
]}

Sander, JWAS ^{[1
]}

机构：

[1] UCL, Inst Neurol, Dept Clin & Expt Epilepsy, London WC1N 3BG, England

来源：

NEUROLOGY | 2003年 / 61卷 / 05期

关键词：

D O I：

10.1212/01.WNL.0000078031.32904.0D

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The prevalence and psychopathologic features of psychiatric adverse events (PAE) in 517 patients taking levetiracetam (LEV) were investigated. Fifty-three (10.1%) patients developed PAE. A significant association was found with previous psychiatric history, history of febrile convulsions, and history of status epilepticus, whereas lamotrigine co-therapy had a protective effect. PAE were not related to the titration schedule of LEV, and certain patients seem to be biologically more vulnerable.

引用

页码：704 / 706

页数：4

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