Enantioselective total synthesis of the phytotoxic lactone herbarumin I

被引：85

作者：

Fürstner, A ^{[1
]}

Radkowski, K ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 07期

关键词：

D O I：

10.1039/b101148k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A concise total synthesis of the potent herbicide herbarumin I (1) is presented based on an (E)-selective RCM reaction forging the 10-membered ring of this macrolide.

引用

页码：671 / 672

页数：2

共 43 条

[11]

Fürstner A, 2000, ANGEW CHEM INT EDIT, V39, P3012

[12]

Fürstner A, 2001, CHEMBIOCHEM, V2, P60

[13] Ring-closing alkyne metathesis.: Stereoselective synthesis of the cytotoxic marine alkaloid motuporamine C [J].

Fürstner, A ;

Rumbo, A .

JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (08) :2608-2611

[14] Mo[N(t-Bu)(Ar)]3 complexes as catalyst precursors:: In situ activation and application to metathesis reactions of alkynes and diynes [J].

Fürstner, A ;

Mathes, C ;

Lehmann, CW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (40) :9453-9454

[15] Ring closing alkyne metathesis.: Comparative investigation of two different catalyst systems and application to the stereoselective synthesis of olfactory lactones, azamacrolides, and the macrocyclic perimeter of the marine alkaloid nakadomarin A [J].

Fürstner, A ;

Guth, O ;

Rumbo, A ;

Seidel, G .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (48) :11108-11113

[16] Coordinatively unsaturated ruthenium allenylidene complexes:: highly effective, well defined catalysts for the ring-closure metathesis of α,ω-dienes and dienynes [J].

Fürstner, A ;

Hill, AF ;

Liebl, M ;

Wilton-Ely, JDET .

CHEMICAL COMMUNICATIONS, 1999, (07) :601-602

[17]

Furstner A, 1997, SYNLETT, P1010

[18]

Fürstner A, 1998, ANGEW CHEM INT EDIT, V37, P1734, DOI 10.1002/(SICI)1521-3773(19980703)37:12<1734::AID-ANIE1734>3.0.CO

[19]

2-6

[20] Recent advancements in ring closing olefin metathesis [J].

Furstner, A .

TOPICS IN CATALYSIS, 1997, 4 (3-4) :285-299

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