Sperry and Hebb: oil and vinegar?

被引:50
作者
Cline, H [1 ]
机构
[1] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
关键词
D O I
10.1016/j.tins.2003.10.005
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The interface between so-called activity-dependent and activity-independent mechanisms of circuit development is discussed here in light of recent findings that question the role of activity in brain development. This debate is presented simplistically here in terms of Sperry's chemoaffinity hypothesis versus Hebb's rules of correlation-based synaptic change, which are often presented as being mutually exclusive - much like oil and vinegar.
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收藏
页码:655 / 661
页数:7
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