Cadmium induced lipid peroxidation and antioxidant enzymes in vitro in human erythrocytes

被引：0
|
作者：
Bansal, AK [1 ]
Bhatnagar, D [1 ]
机构：
[1] DA UNIV, SCH BIOCHEM, INDORE 452001, INDIA
来源：
FRESENIUS ENVIRONMENTAL BULLETIN | 1996年 / 5卷 / 7-8期
关键词：
lipid peroxidation; erythrocytes; cadmium; superoxide dismutase; catalase; glutathione reductase; antioxidants;
D O I：
暂无
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Significantly higher lipid peroxidation (LPO) and lower activities of catalase (CAT) and superoxide dismutase (SOD) in human erythrocytes were observed with the increasing concentrations of cadmium chloride (CdCl2) treatment. But glutathione reductase (GR) enzyme avtivity increased at lower concentrations of CdCl2 treatment. Pretreatment of antioxidants protected the erythrocytes exposed to CdCl2 against hemolysis and LPO. It is likely that cadmium toxicity is due to its pro-oxidant catalytic activity.
引用
收藏
页码：460 / 465
页数：6
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