Cadmium induced lipid peroxidation and antioxidant enzymes in vitro in human erythrocytes

被引：0
|
作者：
Bansal, AK [1 ]
Bhatnagar, D [1 ]
机构：
[1] DA UNIV, SCH BIOCHEM, INDORE 452001, INDIA
来源：
FRESENIUS ENVIRONMENTAL BULLETIN | 1996年 / 5卷 / 7-8期
关键词：
lipid peroxidation; erythrocytes; cadmium; superoxide dismutase; catalase; glutathione reductase; antioxidants;
D O I：
暂无
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Significantly higher lipid peroxidation (LPO) and lower activities of catalase (CAT) and superoxide dismutase (SOD) in human erythrocytes were observed with the increasing concentrations of cadmium chloride (CdCl2) treatment. But glutathione reductase (GR) enzyme avtivity increased at lower concentrations of CdCl2 treatment. Pretreatment of antioxidants protected the erythrocytes exposed to CdCl2 against hemolysis and LPO. It is likely that cadmium toxicity is due to its pro-oxidant catalytic activity.
引用
收藏
页码：460 / 465
页数：6
相关论文
共 50 条
  • [21] Cadmium-induced lipid peroxidation and the antioxidant enzymes in rat tissues: Role of vitamin E and selenium
    Sarkar, S
    Poonam, Y
    Bhatnagar, D
    TRACE ELEMENTS AND ELECTROLYTES, 1997, 14 (01): : 41 - 45
  • [22] Cadmium stress induced changes in antioxidant enzymes, lipid peroxidation and hydrogen peroxide contents in barley seedlings
    Alayat, Amel
    Souiki, Lynda
    Djebar, Mohammed Reda
    Boumedris, Zine Eddine
    Moumeni, Ouissem
    Berrebbah, Houria
    Advance Journal of Food Science and Technology, 2015, 9 (07) : 507 - 513
  • [23] Plasma lipid peroxidation and erythrocyte antioxidant enzymes status in workers exposed to cadmium
    Babu, Kalahasthi Ravi
    Rajmohan, Hirehal Raghavendra Rao
    Rajan, Bagalur Krishna Murthy
    Kumar, M. Karuna
    TOXICOLOGY AND INDUSTRIAL HEALTH, 2006, 22 (08) : 329 - 335
  • [24] The effect of bilirubin on lipid peroxidation and antioxidant enzymes in cumene hydroperoxide-treated erythrocytes
    Yesilkaya, A
    Yegin, A
    Özdem, S
    Aksu, TA
    INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH, 1998, 28 (04): : 230 - 234
  • [25] ACTIVITY OF ANTIOXIDANT ENZYMES AND LIPID-PEROXIDATION IN ERYTHROCYTES OF CHILDREN WITH DIABETES-MELLITUS
    SALNIKOVA, LA
    MUSATOVA, NV
    LOPATINA, NI
    VOPROSY MEDITSINSKOI KHIMII, 1990, 36 (01): : 39 - 41
  • [26] Palm oil induced changes in ocular tissue lipid peroxidation, antioxidant enzymes and ATPases of rabbits in cadmium toxicity
    Eriyamremu, G. E.
    Ojimogho, S. E.
    Asagba, S. O.
    Osagie, V. E.
    FOOD AND CHEMICAL TOXICOLOGY, 2008, 46 (09) : 3155 - 3158
  • [27] Effects of cadmium exposure on digestive enzymes, antioxidant enzymes, and lipid peroxidation in the freshwater crab Sinopotamon henanense
    Wu, Hao
    Xuan, Ruijing
    Li, Yingjun
    Zhang, Xiaomin
    Wang, Qian
    Wang, Lan
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2013, 20 (06) : 4085 - 4092
  • [28] Effects of cadmium exposure on digestive enzymes, antioxidant enzymes, and lipid peroxidation in the freshwater crab Sinopotamon henanense
    Hao Wu
    Ruijing Xuan
    Yingjun Li
    Xiaomin Zhang
    Qian Wang
    Lan Wang
    Environmental Science and Pollution Research, 2013, 20 : 4085 - 4092
  • [29] PROTECTIVE EFFECT OF GLUTATHIONE AND SELENIUM AGAINST ALLOXAN-INDUCED LIPID-PEROXIDATION AND LOSS OF ANTIOXIDANT ENZYMES IN ERYTHROCYTES
    YADAV, P
    SARKAR, S
    BHATNAGAR, D
    JOURNAL OF BIOSCIENCES, 1994, 19 (01) : 19 - 25
  • [30] Antioxidant enzymes activity and lipid peroxidation in liver and kidney of rats exposed to cadmium and ethanol
    Jurczuk, M
    Brzóska, MM
    Moniuszko-Jakoniuk, J
    Galazyn-Sidorczuk, M
    Kulikowska-Karpinska, E
    FOOD AND CHEMICAL TOXICOLOGY, 2004, 42 (03) : 429 - 438
12345