Detection of human pathogenic Ehrlichia muris-like agent in Peromyscus leucopus

被引：19

作者：

Castillo, Caroline G. ^{[1
]}

Eremeeva, Marina E. ^{[2
]}

Paskewitz, Susan M. ^{[3
]}

Sloan, Lynne M. ^{[1
]}

Lee, Xia ^{[3
]}

Irwin, William E. ^{[4
]}

Tonsberg, Stefan ^{[4
]}

Pritt, Bobbi S. ^{[1
]}

机构：

[1] Mayo Clin, Rochester, MN 55905 USA

[2] Ctr Dis Control & Prevent, Atlanta, GA USA

[3] Univ Wisconsin, Madison, WI USA

[4] US Army Publ Hlth Command Reg West, Washington, DC USA

来源：

TICKS AND TICK-BORNE DISEASES | 2015年 / 6卷 / 02期

关键词：

Ehrlichia muris; Ehrlichia muris-like (EML) agent; Ehrlichiosis; Peromyscus; UNITED-STATES; ANAPLASMOSIS; RUSSIA; TICKS;

D O I：

10.1016/j.ttbdis.2014.11.006

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

An Ehrlichia muris-like (EML) bacterium was recently detected in humans and Ixodes scapularis ticks in Minnesota and Wisconsin. The reservoir for this agent is unknown. To investigate the occurrence of the EML agent, groEL PCR testing and sequencing was performed on blood from small mammals and white-tailed deer that were collected in areas where human and tick infections were previously demonstrated. DNA of the EML agent was detected in two Peromyscus leucopus of 146 small mammals (1.4%); while 181 O. virgthianus tested negative. This report provides the first evidence that DNA from the EML agent is found in Peromyscus leucopus, the same animal that is a reservoir for Anaplasma phagocytophilum in this region. The role of white-tailed deer remains inconclusive. Further sampling is warranted to understand the spatial and temporal distribution, transmission and maintenance of this pathogen. (C) 2014 Elsevier GmbH. All rights reserved.

引用

页码：155 / 157

页数：3

共 11 条

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