First case of Neisseria meningitidis capsule null locus infection in China

被引：18
|
作者：
Xu, Zheng [1 ,2 ]
Zhu, Bingqing [1 ,2 ]
Xu, Li [1 ,2 ]
Gao, Yuan [1 ,2 ]
Shao, Zhujun [1 ,2 ,3 ]
机构：
[1] Chinese Ctr Dis Control & Prevent, Natl Inst Communicable Dis Control & Prevent, Beijing, Peoples R China
[2] Chinese Ctr Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing, Peoples R China
[3] Collaborat Innovat Ctr Diag & Treatment Infect Di, Hangzhou, Zhejiang, Peoples R China
来源：
INFECTIOUS DISEASES | 2015年 / 47卷 / 08期
关键词：
Capsule; cnl; Neisseria meningitidis; non-groupable; ST-198; complex; MENINGOCOCCAL DISEASE; STRAIN;
D O I：
10.3109/00365548.2015.1010228
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Invasive meningococcal diseases are rarely caused by capsule null locus (cnl) strains, which are unencapsulated owing to an absence of capsule synthesis genes. Only a few cases of cnl meningococcemia in severely immunocompromised patients have been reported. Here, we describe and discuss the first case of invasive disease in an immunocompetent patient due to a cnl strain of Neisseria meningitidis in China. We characterize this strain and discuss the special ST-198 complex of cnl.
引用
收藏
页码：591 / 592
页数：2
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