Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases

被引：49
作者：
Kim, Jung Min [1 ,2 ]
Cheon, Jae Hee [1 ,2 ,3 ,4 ]
机构：
[1] Yonsei Univ, Dept Internal Med, Coll Med, 50-1 Yonsei Ro, Seoul 03722, South Korea
[2] Yonsei Univ, Inst Gastroenterol, Coll Med, 50-1 Yonsei Ro, Seoul 03722, South Korea
[3] Severance Hosp, Avison Biomed Res Ctr, Seoul, South Korea
[4] Pohang Univ Sci & Technol POSTECH, Affiliate Fac, Pohang, South Korea
来源：
INTESTINAL RESEARCH | 2020年 / 18卷 / 03期
关键词：
Inflammatory bowel diseases; Neuromuscular manifestations; Skin manifestations; Eye manifestations; PRIMARY SCLEROSING CHOLANGITIS; EVIDENCE-BASED CONSENSUS; INNATE LYMPHOID-CELLS; ULCERATIVE-COLITIS; CROHNS-DISEASE; VENOUS THROMBOEMBOLISM; PSORIATIC-ARTHRITIS; SKIN MANIFESTATIONS; DOUBLE-BLIND; TNF-ALPHA;
D O I：
10.5217/ir.2019.00128
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
A considerable number of patients with inflammatory bowel disease (IBD) experience extraintestinal manifestations (EIMs), which can present either before or after IBD diagnosis. Unraveling the pathogenic pathways of EIMs in IBD is challenging because of the lack of reliable criteria for diagnosis and difficulty in distinguishing EIMs from external pathologies caused by drugs or other etiologies. Optimizing treatment can also be difficult. Early diagnosis and management of EIM revolve around multidisciplinary teams, and they should have the resources necessary to make and implement appropriate decisions. In addition, specialists of the affected organs should be trained in IBD treatment. Furthermore, patient awareness regarding the extraintestinal symptoms of IBD is of paramount importance for improving patient understanding of disease and health outcomes. Herein, we review the pathogenesis and clinical perspectives of EIMs in IBD.
引用
收藏
页码：249 / 264
页数：16
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