Statistical methods for 3D reconstruction of viruses using cryo electron microscopy data

被引：0

作者：

Gao, W ^{[1
]}

Doerschuk, PC ^{[1
]}

机构：

[1] Purdue Univ, Sch Elect & Comp Engn, W Lafayette, IN 47907 USA

来源：

BAYESIAN INFERENCE FOR INVERSE PROBLEMS | 1998年 / 3459卷

关键词：

projection; tomography; electron microscopy; viruses; reconstruction;

D O I：

10.1117/12.323797

中图分类号：

O29 [应用数学];

学科分类号：

070104 ;

摘要：

Cryo electron microscopy of viruses provides 2D projections of the scattering intensity of the viral particle but the orientation of the projections is not known. We describe an approach to reconstructing the 3D scattering intensity in spite of the unknown projection orientations using nonlinear least squares ideas where the reconstruction is guaranteed to have the icosahedral symmetry known to be present in the viral particle.

引用

页码：12 / 20

页数：9