Palladium-Catalyzed Oxidative Cyclization of Azulene-2-Carboxylic Acids with 1,3-Dienes for the Synthesis of Alkenyl Azulenolactones

被引：4

作者：

Maeng, Chanyoung ^{[1
]}

Yun, Yongjoo ^{[1
]}

Son, Jeong-Yu ^{[1
]}

Lee, Phil Ho ^{[1
]}

机构：

[1] Kangwon Natl Univ, Dept Chem, Chunchon 24341, South Korea

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2022年 / 364卷 / 16期

基金：

新加坡国家研究基金会;

关键词：

palladium; C-H activation; azulene; 1; 3-diene; azulenolactone; EXPANSION-ANNULATION STRATEGY; ELECTRON-RICH ARENES; SUBSTITUTED AZULENES; BOND ACTIVATION; ACCESS; ARYLATION; ROUTE; HYDROARYLATION; DERIVATIVES; CASCADE;

D O I：

10.1002/adsc.202200452

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

We have developed Pd-catalyzed oxidative cyclization reactions of a wide range of azulene-2-carboxylic acids with a large number of activated as well as unactivated 1,3-dienes, consequently allowing a streamlined synthetic method for the selective preparation of monosubstituted alkenyl dihydroazulenolactones and their derivatives.

引用

页码：2859 / 2864

页数：6

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