Synthesis and biological evaluation of some acyclic 4,6-disubstituted 1H-pyrazolo[3,4-d]pyrimidine nucleosides

被引：3
|
作者：
Moukha-chafiq, O
Taha, ML
Mouma, A
Lazrek, HB
Vasseur, JJ
De Clercq, E
机构：
[1] Fac Sci, Dept Chin, Chim Bioorgan Lab, Agadir 80000, Morocco
[2] Fac Sci 1, Lab Chim Bioorgan, Marrakech, Morocco
[3] UST Montpellier 2, Lab Chim Organ Biomol Synth, Montpellier, France
[4] Katholieke Univ Leuven, Rega Inst Med Res, Louvain, Belgium
来源：
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2003年 / 22卷 / 5-8期
关键词：
acyclic nucleosides; pyrazolo[3,4-d]pyrimidines; biological evaluation;
D O I：
10.1081/NCN-120022697
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The chemical synthesis and biological evaluation of some acyclic alpha-[6-(1'-carbamoylalkylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thioalkylamide nucleosides are described.
引用
收藏
页码：967 / 972
页数：6
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