Synthesis and biological evaluation of some acyclic 4,6-disubstituted 1H-pyrazolo[3,4-d]pyrimidine nucleosides

被引：3

作者：

Moukha-chafiq, O

Taha, ML

Mouma, A

Lazrek, HB

Vasseur, JJ

De Clercq, E

机构：

[1] Fac Sci, Dept Chin, Chim Bioorgan Lab, Agadir 80000, Morocco

[2] Fac Sci 1, Lab Chim Bioorgan, Marrakech, Morocco

[3] UST Montpellier 2, Lab Chim Organ Biomol Synth, Montpellier, France

[4] Katholieke Univ Leuven, Rega Inst Med Res, Louvain, Belgium

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2003年 / 22卷 / 5-8期

关键词：

acyclic nucleosides; pyrazolo[3,4-d]pyrimidines; biological evaluation;

D O I：

10.1081/NCN-120022697

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The chemical synthesis and biological evaluation of some acyclic alpha-[6-(1'-carbamoylalkylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thioalkylamide nucleosides are described.

引用

页码：967 / 972

页数：6

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