An unexpected cause of chorea in an adolescent girl: systemic lupus erythematosus

被引:0
|
作者
Terin, Harun [1 ]
Akcaboy, Meltem [1 ]
Demet, Rukiye [1 ]
Ozdemir, Mehmet Fatih Akif [2 ]
Bulbul, Mehmet [3 ]
Senel, Saliha [1 ]
机构
[1] Dr Sami Ulus Matern & Childrens Hlth & Dis Traini, Dept Pediat, Babur Caddesi 41, Ankara, Turkey
[2] Dr Sami Ulus Matern & Childrens Hlth & Dis Traini, Dept Pediat Neurol, Ankara, Turkey
[3] Dr Sami Ulus Matern & Childrens Hlth & Dis Traini, Dept Pediat Rheumatol, Ankara, Turkey
来源
ZEITSCHRIFT FUR RHEUMATOLOGIE | 2022年 / 81卷 / 04期
关键词
Chorea; Movement disorder; Children;
D O I
10.1007/s00393-021-01070-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Involuntary movement disorders are rare in childhood. Hyperkinetic movement disorders including chorea stand as the leading cause. Although Sydenham chorea is the major diagnosis in most children and adolescents, appropriate differential diagnosis is fundamental for a final decision. A detailed and careful history as well as physical examination is the principal proceeding for accurate diagnosis. Herein, we report on an adolescent girl who was admitted to our hospital with chorea and subsequently diagnosed with systemic lupus erythematosus (SLE). Accompanying joint complaints in the patient's history, including growth retardation noticed during a physical examination and bicytopenia recognized in laboratory evaluation, increased the suspicion of SLE rather than Sydenham chorea in the patient. Central nervous system involvement defined as neuropsychiatric lupus presents wide clinical findings varying from stroke and seizures to psychosis and cognitive dysfunction. Although disease activity, persistently positive anticardiolipin antibodies, and lupus anticoagulant positivity are reported to be the most important risk factors in neuropsychiatric lupus, they are not always directly correlated. We present this patient in order to draw attention to the importance of physical examination and history in the differential diagnosis of chorea in childhood.
引用
收藏
页码:339 / 341
页数:3
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