The potential effect of Polypodium leucotomos extract on ultraviolet- and visible light-induced photoaging

被引:14
作者
Pourang, Aunna [1 ]
Dourra, Mohsen [2 ]
Ezekwe, Nneamaka [1 ]
Kohli, Indermeet [1 ]
Hamzavi, Iltefat [1 ]
Lim, Henry W. [1 ]
机构
[1] Henry Ford Hlth Syst, Photomed & Photobiol Unit, Dept Dermatol, 3031 W Grand Blvd,Suite 800, Detroit, MI 48202 USA
[2] Michigan State Univ, Coll Med, E Lansing, MI USA
关键词
Polypodium leucotomos; Photoaging; Visible light; Ultraviolet light; HYDROPHILIC EXTRACT; LIPID-PEROXIDATION; COMMON DELETION; AQUEOUS EXTRACT; SKIN; EXPRESSION; CELL; RADIATION; ACID; PREVENTION;
D O I
10.1007/s43630-021-00087-x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Photoaging induced by both ultraviolet and visible light has been shown to lead to increased inflammation and dysregulation of the extracellular matrix. Standardized extract of the Polypodium leucotomos fern, PLE, possesses anti-inflammatory and antioxidant properties, and has been shown to potentially mitigate photoaging through various mechanisms. This comprehensive review presents the data available on the effects of P. leucotomos extract on UV and VL-induced photoaging in vitro as well as in vivo in murine and human models.
引用
收藏
页码:1229 / 1238
页数:10
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