RETRACTED: Effects of microRNA-146a on the proliferation and apoptosis of human osteochondrocytes by targeting TRAF6 through the NF- κB signalling pathway (Retracted article. See vol. 41, 2021)

被引：21

作者：

West, Camilla ^{[1
]}

McDermott, Michael F. ^{[1
]}

机构：

[1] Univ Leeds, St James Univ Hosp, LIRMM, Wellcome Trust Brenner Bldg 32840, Leeds, W Yorkshire, England

来源：

BIOSCIENCE REPORTS | 2017年 / 37卷

关键词：

OSTEOARTHRITIS; CHONDROCYTES; EXPRESSION; MIR-146; IRAK1;

D O I：

10.1042/BSR20170180

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

MicroRNAs are important cellular mediators of mRNA degradation and translation repression, which in turn can have an impact on various processes and, if their function is perturbed, can cause disease. Here, we summarize the recent manuscript by Zhong et al. [(2017) Biosci. Rep. 37, BSR20160578], which explores microRNA-146a and how it may play an indirect yet vital role in the proliferation of osteoarthritis (OA) chondrocytes. The data presented by the authors could have important implications for future OA therapies.

引用

页数：3

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