Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections

被引：230

作者：

Lowe, MJ ^{[1
]}

Dzemidzic, M ^{[1
]}

Lurito, JT ^{[1
]}

Mathews, VP ^{[1
]}

Phillips, MD ^{[1
]}

机构：

[1] Indiana Univ, Sch Med, Dept Radiol, Indianapolis, IN 46202 USA

来源：

NEUROIMAGE | 2000年 / 12卷 / 05期

关键词：

functional magnetic resonance imaging; resting state correlation; physiologic noise; working memory; dorsolateral prefrontal cortex;

D O I：

10.1006/nimg.2000.0654

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Cross-correlation of low-frequency temporal fluctuations (<0.08 Hz) was used to correlate widely separated anatomic regions during continuous performance of a spatial working memory task. The regions of highest correlation to right-hemisphere dorsolateral prefrontal cortex correspond to the regions of largest baseline signal change in a conventional block-style functional MRI paradigm. Additionally, it is shown that the correlations between elements of the functional network increase during performance of a task that activates the network when compared to a task that does not directly stimulate the functionally connected network. (C) 2000 Academic Press.

引用

页码：582 / 587

页数：6

共 10 条

[1] FUNCTIONAL CONNECTIVITY IN THE MOTOR CORTEX OF RESTING HUMAN BRAIN USING ECHO-PLANAR MRI [J].

BISWAL, B ;

YETKIN, FZ ;

HAUGHTON, VM ;

HYDE, JS .

MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (04) :537-541

[2] ACTIVATION OF PREFRONTAL CORTEX IN CHILDREN DURING A NONSPATIAL WORKING-MEMORY TASK WITH FUNCTIONAL MRI [J].

CASEY, BJ ;

COHEN, JD ;

JEZZARD, P ;

TURNER, R ;

NOLL, DC ;

TRAINOR, RJ ;

GIEDD, J ;

KAYSEN, D ;

HERTZPANNIER, L ;

RAPOPORT, JL .

NEUROIMAGE, 1995, 2 (03) :221-229

[3] Reproducibility of fMRI results across four institutions using a spatial working memory task [J].

Casey, BJ ;

Cohen, JD ;

O'Craven, K ;

Davidson, RJ ;

Irwin, W ;

Nelson, CA ;

Noll, DC ;

Hu, XP ;

Lowe, MJ ;

Rosen, BR ;

Truwitt, CL ;

Turski, P .

NEUROIMAGE, 1998, 8 (03) :249-261

[4] Temporal and spatial MRI responses to subsecond visual activation [J].

Fransson, P ;

Krüger, G ;

Merboldt, KD ;

Frahm, J .

MAGNETIC RESONANCE IMAGING, 1999, 17 (01) :1-7

[5]

FRIEDMAN HR, 1994, J NEUROSCI, V14, P2775

[6]

GOLDMANRAKIC PS, 1993, BRAIN MECH PERCEPTIO, V1, P445

[7] Treatment of baseline drifts in fMRI time series analysis [J].

Lowe, MJ ;

Russell, DP .

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1999, 23 (03) :463-473

[8] Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations [J].

Lowe, MJ ;

Mock, BJ ;

Sorenson, JA .

NEUROIMAGE, 1998, 7 (02) :119-132

[9] FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF HUMAN PREFRONTAL CORTEX ACTIVATION DURING A SPATIAL WORKING-MEMORY TASK [J].

MCCARTHY, G ;

BLAMIRE, AM ;

PUCE, A ;

NOBRE, AC ;

BLOCH, G ;

HYDER, F ;

GOLDMANRAKIC, P ;

SHULMAN, RG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (18) :8690-8694

[10] Load-dependent roles of frontal brain regions in the maintenance of working memory [J].

Rypma, B ;

Prabhakaran, V ;

Desmond, JE ;

Glover, GH ;

Gabrieli, JDE .

NEUROIMAGE, 1999, 9 (02) :216-226

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