C19-diterpenoid alkaloids from Aconitum hemsleyanum var. circinatum

被引：6

作者：

Xu, Jin-bu ^{[1
,2
]}

Huang, Shuai ^{[1
]}

Zhou, Xian-li ^{[1
,2
]}

机构：

[1] Southwest Jiaotong Univ, Sch Life Sci & Engn, Chengdu 610031, Sichuan, Peoples R China

[2] Southwest Jiaotong Univ, Key Lab Adv Technol Mat, Minist Educ, Sch Mat Sci & Engn, Chengdu 610031, Sichuan, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2018年 / 27卷

关键词：

Aconitum hemsleyanum var circinatum; Ranunculaceae; Diterpenoid alkaloids; Cytotoxicity; REVISION;

D O I：

10.1016/j.phytol.2018.07.012

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Six new C-19-diterpenoid alkaloids, circinatines A-F (1-6), along with eight known compounds, were isolated from the roots of Aconitum hemsleyanum var. circinatum. Their structures were elucidated by extensive spectroscopic methods including NMR, IR, HR-ESI-MS and X-ray experiments. All compounds were evaluated for their cytotoxic activity against MCF-7, A549, HCT-116 and 786-0 human cancer cell lines.

引用

页码：178 / 182

页数：5

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