Patterns of chronic hepatitis B in Central Italy: a cross-sectional study

被引：14

作者：

Piccolo, Paola ^{[1
]}

Lenci, Ilaria

Telesca, Claudia

Di Paolo, Daniele

Bandiera, Franco ^{[2
]}

De Melia, Luigi ^{[3
]}

Sorbello, Orazio ^{[3
]}

Renier, Giuseppina ^{[4
]}

Ricci, Giovanni L. ^{[5
]}

Nosotti, Lorenzo ^{[6
]}

Romano, Mario ^{[7
]}

De Santis, Adriano ^{[5
]}

Levrero, Massimo ^{[5
]}

Antonucci, Giorgio ^{[8
]}

Longo, Maria Antonella ^{[8
]}

Annicchiarico, Brigida E. ^{[9
]}

机构：

[1] Univ Roma Tor Vergata, Hepatol Unit, Dept Internal Med, I-00133 Rome, Italy

[2] SS Annunziata Gen Hosp, Sassari, Italy

[3] Cagliari Univ Hosp, Cagliari, Italy

[4] Carbonia Gen Hosp, Carbonia, Italy

[5] La Sapienza Univ Hosp, Rome, Italy

[6] S Gallicano Gen Hosp, Rome, Italy

[7] Pertini Gen Hosp, Rome, Italy

[8] Spallanzani Natl Inst Infect Dis, Rome, Italy

[9] Catholic Univ Hosp, Rome, Italy

来源：

EUROPEAN JOURNAL OF PUBLIC HEALTH | 2010年 / 20卷 / 06期

关键词：

HBV DNA; HCV co-infection; HDV co-infection; hepatitis B virus; inactive HBsAg carrier; VACCINATION; MULTICENTER; PREVALENCE; ETIOLOGY; UPDATE;

D O I：

10.1093/eurpub/ckp168

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We investigated the patterns of chronic hepatitis B virus (HBV)-related disease in a large cohort of HBsAg-positive patients, in Central Italy, by collecting a screening form with demographic, clinical and laboratory data. Overall, 737 HBsAg-positive cases were included (70% male; median age 52 years): 30% were inactive HBsAg carriers, 51% had chronic hepatitis B (CHB) and 19% had HBV-related cirrhosis. Patients from non-European Union (EU) countries (n = 65) were significantly younger, had a higher prevalence of HBeAg-positive infection and hepatitis delta virus (HDV) co-infection than patients of Italian origin. Therefore, as immigration from non-EU countries continues to grow, we can expect a change in the landscape of HBV-related disease in our area.

引用

页码：711 / 713

页数：3

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