Therapeutic management of neonatal chylous ascites: report of a case and review of the literature

被引：30

作者：

Karagol, Belma Saygili ^{[1
]}

Zenciroglu, Aysegul ^{[1
]}

Gokce, Selim ^{[2
]}

Kundak, Ahmet Afsin ^{[1
]}

Ipek, Mehmet Sah ^{[1
]}

机构：

[1] Childrens Educ & Res Hosp, Div Neonatol, Ankara, Turkey

[2] Childrens Educ & Res Hosp, Div Pediat Gastroenterol & Nutr, Ankara, Turkey

来源：

ACTA PAEDIATRICA | 2010年 / 99卷 / 09期

关键词：

Chylous ascites; Lymphatic leakage; Medium-chain triglycerides; Neonate; Octreotide; TOTAL PARENTERAL-NUTRITION; SOMATOSTATIN ANALOG; LYMPHATIC DYSPLASIA; CHILDREN; DIAGNOSIS; MALROTATION; CHYLOTHORAX; RESOLUTION; ETIOLOGY; INFANTS;

D O I：

10.1111/j.1651-2227.2010.01818.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Congenital chylous ascites is a rare condition seen in the neonatal period and the data on pathogenesis and treatment modalities are limited. In this article, we report a case of neonate with chylous ascites and review the therapeutic management procedures on chylous ascites in childhood. We present our experience in the diagnosis and treatment of this condition. Conclusion: Medium-chain triglycerides (MCT)-based diet can be tried as a first option in chylous ascites treatment. In resistant or unresponsive cases, somatostatin along with TPN can have use in closing the lymphatic leakage or relieving the symptoms effectively and rapidly. Conventional regimens including enteral feeding with MCT-based formula can then be re-administered as a maintenance treatment after reduction of lymph flow with the use of total parenteral nutrition (TPN) and somatostatin infusion combination. Patient-specific approach should be attempted for chylous ascites caused by various disorders and started as soon as possible.

引用

页码：1307 / 1310

页数：4

共 48 条

[11]

CHANG SHT, 1980, J PEDIATR SURG, V15, P748

[12] Neonatal chylous ascites - report of three cases and review of the literature [J].

J. K. Chye ;

C. T. Lim ;

M. Van der Heuvel .

Pediatric Surgery International, 1997, 12 (4) :296-298

[13] CHYLOUS ASCITES IN INFANTS AND CHILDREN - A CASE-REPORT AND LITERATURE-REVIEW [J].

COCHRAN, WJ ;

KLISH, WJ ;

BROWN, MR ;

LYONS, JM ;

CURTIS, T .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1985, 4 (04) :668-673

[14] Conservative treatment of postsurgical lymphatic leaks with somatostatin-14 [J].

Collard, JM ;

Laterre, PF ;

Boemer, F ;

Reynaert, M ;

Ponlot, R .

CHEST, 2000, 117 (03) :902-905

[15] CONGENITAL CHYLOUS ASCITES - LYMPHANGIOGARAPHIC DEMONSTRATION OF OBSTRUCTION OF CISTERNA CHYLI AND CHYLOUS REFLUX INTO PERITONEAL SPACE AND SMALL INTESTINE [J].

CRAVEN, CE ;

GOLDMAN, AS ;

LARSON, DL ;

PATTERSON, M ;

HENDRICK, CK .

JOURNAL OF PEDIATRICS, 1967, 70 (3P1) :340-+

[16]

DAGASTINO S, 1998, PEDIAT MED CHIR, V20, P285

[17] TOTAL PARENTERAL-NUTRITION IN THE MANAGEMENT OF TRAUMATIC CHYLOUS ASCITES IN INFANCY [J].

DILLARD, RP ;

STEWART, AG .

CLINICAL PEDIATRICS, 1985, 24 (05) :290-292

[18]

EVERS KG, 1977, MONATSSCHR KINDERH, V125, P526

[19] CHYLOUS ASCITES IN SIBS FROM A CONSANGUINEOUS MARRIAGE [J].

FLORES, S ;

LEUNGAS, J ;

ARREDONDOVEGA, F ;

GUIZARVAZQUEZ, J .

AMERICAN JOURNAL OF MEDICAL GENETICS, 1979, 3 (02) :145-148

[20] Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1 [J].

Gale, NW ;

Thurston, G ;

Hackett, SF ;

Renard, R ;

Wang, Q ;

McClain, J ;

Martin, C ;

Witte, C ;

Witte, MH ;

Jackson, D ;

Suri, C ;

Campochiaro, PA ;

Wiegand, SJ ;

Yancopoulos, GD .

DEVELOPMENTAL CELL, 2002, 3 (03) :411-423

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