BINOL: A versatile chiral reagent

被引：919

作者：

Brunel, JM ^{[1
]}

机构：

[1] Univ Paul Cezanne, Fac Sci & Tech St Jerome, INRA, IMRN 1111,Lab SESNAB, F-13397 Marseille 20, France

来源：

CHEMICAL REVIEWS | 2005年 / 105卷 / 03期

关键词：

D O I：

10.1021/cr040079g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The last 20 years witnessed an exclusive growth of research in the field of asymmetric synthesis. This review deals with the synthesis and resolution of BINOL, as well as its use as chiral reagent or ligand. First, the different methods of preparation of racemic and enantiopure BINOL and its application as a ligand or chiral auxiliary in enantioselective reduction or oxidation reactions are described. Second, the C-C bond forming reactions, catalyzed or not, involving BINOL as a reagent or ligand are outlined.

引用

页码：857 / 897

页数：41