共 19 条
Fate of Patients With Prehospital Resuscitation for ST-Elevation Myocardial Infarction and a High Rate of Early Reperfusion Therapy (Results from the PREMIR [Prehospital Myocardial Infarction Registry])
被引:20
作者:

Koeth, Oliver
论文数: 0 引用数: 0
h-index: 0
机构:
Klinikum Worms, Worms, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Nibbe, Lutz
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h-index: 0
机构:
Charite, Berlin, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Arntz, Hans-Richard
论文数: 0 引用数: 0
h-index: 0
机构:
Charite, Berlin, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Dirks, Burkhard
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Ulm Klinikum, Ulm, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Ellinger, Klaus
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机构:
Klinikum Ravensburg, Ravensburg, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Genzwuerker, Harald
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机构:
Kreiskrankenhaus Buchen, Buchen, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Tebbe, Ulrich
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机构:
Klinikum Lippe Detmold, Lippe Detmold, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Schneider, Steffen
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h-index: 0
机构:
Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Friedrich, Joerg
论文数: 0 引用数: 0
h-index: 0
机构:
Klinikum Ludwigshafen, Ludwigshafen, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Zahn, Ralf
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h-index: 0
机构:
Klinikum Ludwigshafen, Ludwigshafen, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany

Zeymer, Uwe
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h-index: 0
机构:
Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany
Klinikum Ludwigshafen, Ludwigshafen, Germany Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany
机构:
[1] Heidelberg Univ, Inst Herzinfarktforsch Ludwigshafen, Heidelberg, Germany
[2] Klinikum Worms, Worms, Germany
[3] Charite, Berlin, Germany
[4] Univ Ulm Klinikum, Ulm, Germany
[5] Klinikum Ravensburg, Ravensburg, Germany
[6] Kreiskrankenhaus Buchen, Buchen, Germany
[7] Klinikum Lippe Detmold, Lippe Detmold, Germany
[8] Klinikum Ludwigshafen, Ludwigshafen, Germany
关键词:
CARDIOPULMONARY-RESUSCITATION;
THROMBOLYTIC THERAPY;
EFFICACY;
MORTALITY;
SAFETY;
D O I:
10.1016/j.amjcard.2012.02.013
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Patients with acute ST-segment elevation myocardial infarction (STEMI) needing prehospital cardiopulmonary resuscitation (CPR) have a very high adverse-event rate. However, little is known about the fate of these patients and predictors of mortality in the era of early reperfusion therapy. From March 2003 through December 2004, 2,317 patients with prehospital diagnosed STEMI were enrolled in the Prehospital Myocardial Infarction Registry. One hundred ninety patients (8.2%) underwent prehospital CPR and were included in our analysis. Overall 90% of patients were treated with early reperfusion therapy, 56.3% received prehospital thrombolysis and 1/2 of these patients received early percutaneous coronary intervention after thrombolysis, 28.4% of patients were treated with primary percutaneous coronary intervention, and 5.3% received in-hospital thrombolysis. Total mortality was 40.0%. The highest mortality was seen in patients with asystole (63%) or pulseless electric activity (64%). Independent predictors of mortality were need for endotracheal intubation and older age, whereas ventricular fibrillation as initial heart rhythm was associated with survival. In conclusion, in this large registry with prehospital diagnosed STEM I, incidence of prehospital CPR was about 8%. Even with a very high rate of early reperfusion therapy, in-hospital mortality was high. Especially in elderly patients with asystole as initial heart rhythm and with need for endotracheal intubation, prognosis is poor despite aggressive reperfusion therapy. (C) 2012 Elsevier Inc. All rights reserved. (Am J Cardiol 2012;109:1733-1737)
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页码:1733 / 1737
页数:5
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机构:
James Cook Univ Hosp, Middlesbrough, Cleveland, England Royal United Hosp, Bath BA1 3NG, Avon, England

Bottiger, Bernd
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Univ Klinikum Koln, Cologne, Germany Royal United Hosp, Bath BA1 3NG, Avon, England