Efficient aryl-(hetero)aryl coupling by activation of C-Cl and C-F bonds using nickel complexes of air-stable phosphine oxides

被引：226

作者：

Ackermann, L ^{[1
]}

Born, R ^{[1
]}

Spatz, JH ^{[1
]}

Meyer, D ^{[1
]}

机构：

[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 44期

关键词：

D O I：

10.1002/anie.200501860

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A couple of couplings: Air-stable diamino-and dioxophosphine oxides are used as preligands in the nickel-catalyzed Kumada cross-coupling reactions of aryl Grignard reagents. A sterically hindered preligand allows for highly efficient cross-coupling of aryl fluorides at ambient temperature (acac = acetylacetonate). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7216 / 7219

页数：4

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