4-{[5-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl}-N-ethylpiperazine-1-carboxamide

The asymmetric unit of the title compound, C23H23ClFN5O2, contains two crystallographically independent molecules. In one molecule, the pyrazole ring makes dihedral angles of 43.93 (7) and 35.82 (7)degrees, respectively, with the fluoro-and chloro-substituted benzene rings, while the corresponding angles in the other molecule are 52.26 (8) and 36.85 (7)degrees. The piperazine rings adopt chair conformations. In the crystal, adjacent molecules are connected via intermolecular N-H center dot center dot center dot O, C-H center dot center dot center dot F, C-H center dot center dot center dot N and C-H center dot center dot center dot O hydrogen bonds, forming a two-dimensional network parallel to the bc plane. The crystal structure is further stabilized by a weak pi-pi interaction with a centroid-centroid distance of 3.6610 (8) angstrom and by C-H center dot center dot center dot pi interactions.