Selectins facilitate carcinoma metastasis and heparin can prevent them

被引：61

作者：

Borsig, L ^{[1
]}

机构：

[1] Univ Zurich, Inst Physiol, CH-8057 Zurich, Switzerland

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 2004年 / 19卷

关键词：

D O I：

10.1152/nips.01450.2003

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Selectins are cell adhesion molecules mediating attachment of leukocytes to activated endothelium, as well as the adhesion reaction of tumors during malignancy. Heparin, which is known to attenuate metastasis, is a potent blocker of selectins. Here, the role of selectins in metastasis and the potential of heparin to modulate malignancy are discussed

引用

页码：16 / 21

页数：6

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