TREATMENT OF ELDERLY NEWLY DIAGNOSED MULTIPLE MYELOMA PATIENTS: NEW THERAPEUTIC INDICATIONS

被引：0

作者：

Bringhen, S. ^{[1
]}

Bonello, F. ^{[1
]}

机构：

[1] Univ Torino, Azienda Osped Univ Citta Salute & Sci Torino, SSD Clin Trials Oncoematol & Mieloma Multiplo, Div Hematol, Turin, Italy

来源：

HAEMATOLOGICA | 2021年 / 106卷 / 10期

关键词：

OPEN-LABEL; DEXAMETHASONE; LENALIDOMIDE; BORTEZOMIB; SURVIVAL; PHASE-3;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：211 / 215

页数：5

共 14 条

[1] Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial [J].

Drayson, Mark T. ;

Bowcock, Stella ;

Planche, Tim ;

Iqbal, Gulnaz ;

Pratt, Guy ;

Yong, Kwee ;

Wood, Jill ;

Raynes, Kerry ;

Higgins, Helen ;

Dawkins, Bryony ;

Meads, David ;

Hulme, Claire T. ;

Monahan, Irene ;

Karunanithi, Kamaraj ;

Dignum, Helen ;

Belsham, Edward ;

Neilson, Jeff ;

Harrison, Beth ;

Lokare, Anand ;

Campbell, Gavin ;

Hamblin, Michael ;

Hawkey, Peter ;

Whittaker, Anna C. ;

Low, Eric ;

Dunn, Janet A. .

LANCET ONCOLOGY, 2019, 20 (12) :1760-1772

[2] Longer term follow-up of the randomized phase III trial SWOG S0777: bortezomib, lenalidomide and dexamethasone vs. lenalidomide and dexamethasone in patients (Pts) with previously untreated multiple myeloma without an intent for immediate autologous stem cell transplant (ASCT) [J].

Durie, Brian G. M. ;

Hoering, Antje ;

Sexton, Rachael ;

Abidi, Muneer H. ;

Epstein, Joshua ;

Rajkumar, S. Vincent ;

Dispenzieri, Angela ;

Kahanic, Stephen P. ;

Thakuri, Mohan C. ;

Reu, Frederic J. ;

Reynolds, Christopher M. ;

Orlowski, Robert Z. ;

Barlogie, Bart .

BLOOD CANCER JOURNAL, 2020, 10 (05)

[3] Oral ixazomib, lenalidomide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma [J].

Facon, Thierry ;

Venner, Christopher P. ;

Bahlis, Nizar J. ;

Offner, Fritz ;

White, Darrell J. ;

Karlin, Lionel ;

Benboubker, Lotfi ;

Rigaudeau, Sophie ;

Rodon, Philippe ;

Voog, Eric ;

Yoon, Sung-Soo ;

Suzuki, Kenshi ;

Shibayama, Hirohiko ;

Zhang, Xiaoquan ;

Twumasi-Ankrah, Philip ;

Yung, Godwin ;

Rifkin, Robert M. ;

Moreau, Philippe ;

Lonial, Sagar ;

Kumar, Shaji K. ;

Richardson, Paul G. ;

Rajkumar, S. Vincent .

BLOOD, 2021, 137 (26) :3616-3628

[4] Carfilzomib or bortezomib in combination with lenalidomide and dexamethasone for patients with newly diagnosed multiple myeloma without intention for immediate autologous stem-cell transplantation (ENDURANCE): a multicentre, open-label, phase 3, randomised, controlled trial [J].

Kumar, Shaji K. ;

Jacobus, Susanna J. ;

Cohen, Adam D. ;

Weiss, Matthias ;

Callander, Natalie ;

Singh, Avina K. ;

Parker, Terri L. ;

Menter, Alexander ;

Yang, Xuezhong ;

Parsons, Benjamin ;

Kumar, Pankaj ;

Kapoor, Prashant ;

Rosenberg, Aaron ;

Zonder, Jeffrey A. ;

Faber, Edward, Jr. ;

Lonial, Sagar ;

Anderson, Kenneth C. ;

Richardson, Paul G. ;

Orlowski, Robert Z. ;

Wagner, Lynne, I ;

Rajkumar, S. Vincent .

LANCET ONCOLOGY, 2020, 21 (10) :1317-1330

[5]

Kumar SK., 2019, Blood

[6] Dose/schedule-adjusted Rd-R vs continuous Rd for elderly, intermediate-fit patients with newly diagnosed multiple myeloma [J].

Larocca, Alessandra ;

Bonello, Francesca ;

Gaidano, Gianluca ;

D'Agostino, Mattia ;

Offidani, Massimo ;

Cascavilla, Nicola ;

Capra, Andrea ;

Benevolo, Giulia ;

Tosi, Patrizia ;

Galli, Monica ;

Marasca, Roberto ;

Giuliani, Nicola ;

Bernardini, Annalisa ;

Antonioli, Elisabetta ;

Rota-Scalabrini, Delia ;

Cellini, Claudia ;

Pompa, Alessandra ;

Monaco, Federico ;

Patriarca, Francesca ;

di Toritto, Tommaso Caravita ;

Corradini, Paolo ;

Tacchetti, Paola ;

Boccadoro, Mario ;

Bringhen, Sara .

BLOOD, 2021, 137 (22) :3027-3036

[7] First-line therapy with either bortezomib-melphalan-prednisone or lenalidomide-dexamethasone followed by lenalidomide for transplant-ineligible multiple myeloma patients: a pooled analysis of two randomized trials [J].

Larocca, Alessandra ;

Mina, Roberto ;

Offidani, Massimo ;

Liberati, Anna Marina ;

Ledda, Antonio ;

Patriarca, Francesca ;

Evangelista, Andrea ;

Spada, Stefano ;

Benevolo, Giulia ;

Oddolo, Daniela ;

Innao, Vanessa ;

Cangiolosi, Clotilde ;

Bernardini, Annalisa ;

Musto, Pellegrino ;

Amico, Valeria ;

Fraticelli, Vincenzo ;

Paris, Laura ;

Giuliani, Nicola ;

Falcone, Antonietta Pia ;

Zambello, Renato ;

De Paoli, Lorenzo ;

Romano, Alessandra ;

Palumbo, Antonio ;

Montefusco, Vittorio ;

Hajek, Roman ;

Boccadoro, Mario ;

Bringhen, Sara .

HAEMATOLOGICA, 2020, 105 (04) :1074-1080

[8] Patient-centered practice in elderly myeloma patients: an overview and consensus from the European Myeloma Network (EMN) [J].

Larocca, Alessandra ;

Dold, Sandra Maria ;

Zweegman, Sonja ;

Terpos, Evangelos ;

Waesch, Ralph ;

D'Agostino, Mattia ;

Scheubeck, Sophia ;

Goldschmidt, Hartmut ;

Gay, Francesca ;

Cavo, Michele ;

Ludwig, Heinz ;

Straka, Christian ;

Bringhen, Sara ;

Auner, Holger W. ;

Caers, Jo ;

Gramatzki, Martin ;

Offidani, Massimo ;

Dimopoulos, Meletios A. ;

Einsele, Hermann ;

Boccadoro, Mario ;

Sonneveld, Pieter ;

Engelhardt, Monika .

LEUKEMIA, 2018, 32 (08) :1697-1712

[9] Daratumumab Plus Bortezomib, Melphalan, and Prednisone Versus Bortezomib, Melphalan, and Prednisone in Transplant-Ineligible Newly Diagnosed Multiple Myeloma: Frailty Subgroup Analysis of ALCYONE [J].

Mateos, Maria-Victoria ;

Dimopoulos, Meletios A. ;

Cavo, Michele ;

Suzuki, Kenshi ;

Knop, Stefan ;

Doyen, Chantal ;

Lucio, Paulo ;

Nagy, Zsolt ;

Pour, Ludek ;

Grosicki, Sebastian ;

Crepaldi, Andre ;

Liberati, Anna Marina ;

Campbell, Philip ;

Yoon, Sung-Soo ;

Iosava, Genadi ;

Fujisaki, Tomoaki ;

Garg, Mamta ;

Iida, Shinsuke ;

Blade, Joan ;

Ukropec, Jon ;

Pei, Huiling ;

Van Rampelbergh, Rian ;

Kudva, Anupa ;

Qi, Ming ;

San-Miguel, Jesus .

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2021, 21 (11) :785-798

[10] Overall survival with daratumumab, bortezomib, melphalan, and prednisone in newly diagnosed multiple myeloma (ALCYONE): a randomised, open-label, phase 3 trial [J].

Mateos, Maria-Victoria ;

Cavo, Michele ;

Blade, Joan ;

Dimopoulos, Meletios A. ;

Suzuki, Kenshi ;

Jakubowiak, Andrzej ;

Knop, Stefan ;

Doyen, Chantal ;

Lucio, Paulo ;

Nagy, Zsolt ;

Pour, Ludek ;

Cook, Mark ;

Grosicki, Sebastian ;

Crepaldi, Andre ;

Liberati, Anna Marina ;

Campbell, Philip ;

Shelekhova, Tatiana ;

Yoon, Sung-Soo ;

Iosava, Genadi ;

Fujisaki, Tomoaki ;

Garg, Mamta ;

Krevvata, Maria ;

Chen, Ying ;

Wang, Jianping ;

Kudva, Anupa ;

Ukropec, Jon ;

Wroblewski, Susan ;

Qi, Ming ;

Kobos, Rachel ;

San-Miguel, Jesus .

LANCET, 2020, 395 (10218) :132-141

← 1 2 →