SU-8 cantilevers for bio/chemical sensing;: Fabrication, characterisation and development of novel read-out methods

被引:109
作者
Nordstrom, Maria [1 ]
Keller, Stephan [1 ]
Lillemose, Michael [1 ]
Johansson, Alicia
Dohn, Soren [1 ]
Haefliger, Daniel
Blagoi, Gabriela [1 ]
Havsteen-Jakobsen, Mogens [1 ]
Boisen, Anja [1 ]
机构
[1] Tech Univ Denmark, MIC, Dept Micro & Nanotechnol, DK-2800 Lyngby, Denmark
关键词
SU-8; cantilever based sensing; label-free;
D O I
10.3390/s8031595
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Here, we present the activities within our research group over the last five years with cantilevers fabricated in the polymer SU-8. We believe that SU-8 is an interesting polymer for fabrication of cantilevers for bio/chemical sensing due to its simple processing and low Young's modulus. We show examples of different integrated read-out methods and their characterisation. We also show that SU-8 cantilevers have a reduced sensitivity to changes in the environmental temperature and pH of the buffer solution. Moreover, we show that the SU-8 cantilever surface can be functionalised directly with receptor molecules for analyte detection, thereby avoiding gold-thiol chemistry.
引用
收藏
页码:1595 / 1612
页数:18
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