Colchicine for the prevention of the postpericardiotomy syndrome: The COPPS trial

被引：12

作者：

Imazio, Massimo ^{[1
]}

Cecchl, Enrico ^{[1
]}

Trinchero, Rita ^{[1
]}

机构：

[1] Maria Vittoria Hosp, Dept Cardiol, Turin, Italy

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2007年 / 121卷 / 02期

关键词：

postpericardiotomy syndrome; pericarditis; colchicine; prevention;

D O I：

10.1016/j.ijcard.2006.08.071

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Preliminary data have shown that colchicine may be considered for the prevention of the postpericardiotomy syndrome (PPS). The COlchicine for the Prevention of Post-pericardiotomy Syndrome (COPPS) study is a multicenter, double blind, placebo-controlled, randomized trial that will enroll 360 patients after cardiac surgery. The primary end point will be the PSS rate at 12 months. The study will be the first large randomized placebo-controlled trial in this area, and will provide important evidence regarding the possible benefit of colchicine for the primary prevention of the PPS. (C) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：198 / 199

页数：2