Rituximab combined with CHOP for successful treatment of aggressive recurrent, pediatric B-cell large cell non-Hodgkin's lymphoma

被引:2
作者
Jetsrisuparb, A [1 ]
Wiangnon, S
Komvilaisak, P
Kularbkaew, C
Yutanawiboonchai, W
Mairieng, E
机构
[1] Khon Kaen Univ, Fac Med, Dept Pediat, Khon Kaen 40002, Thailand
[2] Khon Kaen Univ, Fac Med, Dept Pathol, Khon Kaen 40002, Thailand
[3] Khon Kaen Univ, Fac Med, Dept Radiol, Khon Kaen 40002, Thailand
关键词
rituximab; aggressive recurrent non-Hodgkin's lymphoma; pediatric patient; anti-CD20 monoclonal antibody; CD20-positive B-cell large cell non-Hodgkin's lymphoma;
D O I
10.1097/01.mph.0000158089.92165.a8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This report is the first to describe the successful treatment of a 14-year-old boy with aggressive recurrent, CD20-positive, B-cell large cell non-Hodgkin's lymphoma. The patient responded to three 4-week courses of rituximab (MabThera) given every 6 months and six cycles of CHOP given every 3 weeks in addition to a modified BFM 86 protocol. Transient neutropenia and lymphopenia occurred but with no clinical significance. The boy has been disease-free for the last 48 months (after 64 months of follow-up); his organ functions are normal. Rituximab and CHOP in addition to chemotherapy may be an alternative treatment for aggressive recurrent, pediatric CD20-positive B-cell large cell non-Hodgkin's lymphoma if highly intensive chemotherapy and stem cell transplantation are not available.
引用
收藏
页码:223 / 226
页数:4
相关论文
共 50 条
  • [21] Evidence-based follow-up in patients with Hodgkin's lymphoma and aggressive B-cell non-Hodgkin's lymphoma
    Spanberger, Thomas
    MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY, 2020, 13 (01) : 55 - 59
  • [22] Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphoma
    S M Ansell
    H Tang
    P J Kurtin
    P A Koenig
    G S Nowakowski
    D A Nikcevich
    G D Nelson
    Z Yang
    D M Grote
    S C Ziesmer
    P T Silberstein
    C Erlichman
    T E Witzig
    Leukemia, 2012, 26 : 1046 - 1052
  • [23] Efficacy and safety of lenalidomide in the treatment of B-cell non-Hodgkin lymphoma
    Liu, Yang
    Li, Yanju
    Zhang, Chike
    Yang, Xu
    Yang, Bo
    Cheng, Jinyang
    Chen, Juan
    Yuan, Xiaoshuang
    Li, Ya
    Chen, Ying
    Zhang, Fengqi
    Tang, Dongxin
    He, Zhixu
    Wang, Feiqing
    DISCOVER ONCOLOGY, 2024, 15 (01)
  • [24] Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphoma
    Ansell, S. M.
    Tang, H.
    Kurtin, P. J.
    Koenig, P. A.
    Nowakowski, G. S.
    Nikcevich, D. A.
    Nelson, G. D.
    Yang, Z.
    Grote, D. M.
    Ziesmer, S. C.
    Silberstein, P. T.
    Erlichman, C.
    Witzig, T. E.
    LEUKEMIA, 2012, 26 (05) : 1046 - 1052
  • [25] Combined therapy with rituximab plus cyclophosphamide/Vincristine/Prednisone for Sjogren's syndrome - associated B-Cell non-Hodgkin's lymphoma
    Carbone, J.
    Perez-Fernandez, R.
    Munoz, A.
    Sabin, P.
    Carreno, L.
    Fernandez-Cruz, E.
    CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2008, 34 (01) : 80 - 84
  • [26] Current Opinion on Pixantrone in the Treatment of Non-Hodgkin B-Cell Lymphoma
    Novakovic, Barbara Jezersek
    Boltezar, Lucka
    Novakovic, Aleksander
    THERAPEUTICS AND CLINICAL RISK MANAGEMENT, 2021, 17 : 183 - 192
  • [27] Novel Therapies Potentially Available for Pediatric B-Cell Non-Hodgkin Lymphoma
    Harker-Murray, Paul D.
    Pommert, Lauren
    Barth, Matthew J.
    JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2020, 18 (08): : 1125 - 1134
  • [28] Complete atrioventricular block induced by rituximab in monotherapy in an aged patient with non-Hodgkin’s diffuse large B-cell lymphoma
    José Manuel Cervera Grau
    Gaspar Esquerdo Galiana
    Ana Belso Candela
    Cristina Llorca Ferrándiz
    Asunción Juárez Marroquí
    Sonia Maciá Escalante
    Clinical and Translational Oncology, 2008, 10 : 298 - 299
  • [29] Complete atrioventricular block induced by rituximab in monotherapy in an aged patient with non-Hodgkin's diffuse large B-cell lymphoma
    Cervera Grau, Jose Manuel
    Esquerdo Galiana, Gaspar
    Belso Candela, Ana
    Llorca Ferrandiz, Cristina
    Juarez Marroqui, Asuncion
    Macia Escalante, Sonia
    CLINICAL & TRANSLATIONAL ONCOLOGY, 2008, 10 (05) : 298 - 299
  • [30] Non-Hodgkin Lymphomas: Impact of Rituximab on Overall Survival of Patients with Diffuse Large B-Cell and Follicular Lymphoma
    Carlos Jaime-Perez, Jose
    Magdalena Gamboa-Alonso, Carmen
    Vazquez-Mellado de larracoechea, Alberto
    Rodriguez-Martinez, Marisol
    Homero Gutierrez-Aguirre, Cesar
    Javier Marfil-Rivera, Luis
    Gomez-Almaguer, David
    ARCHIVES OF MEDICAL RESEARCH, 2015, 46 (06) : 454 - 461