Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, South Korea

被引：13

作者：

Yi, Hwajung ^{[1
]}

Lee, Joo-Yeon ^{[1
]}

Hong, Eun-Hye ^{[1
]}

Kim, Mi-Seon ^{[1
]}

Kwon, Donghyok ^{[1
]}

Choi, Jang-Hoon ^{[1
]}

Choi, Woo-Young ^{[1
]}

Kim, Ki-Soon ^{[1
]}

Lee, Jong-Koo ^{[1
]}

Oh, Hee-Bok ^{[1
]}

Kang, Chun ^{[1
]}

机构：

[1] Korea Ctr Dis Control & Prevent, Natl Inst Hlth, Ctr Infect Dis, Div Influenza Viruses, Seoul 122701, South Korea

来源：

EMERGING INFECTIOUS DISEASES | 2010年 / 16卷 / 12期

关键词：

INFLUENZA-VIRUSES; SUSCEPTIBILITY;

D O I：

10.3201/eid1612.100600

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To identify oseltamivir resistance we analyzed neuraminidase H275Y mutations in samples from 10 patients infected with pandemic (H1N1) 2009 virus in South Korea who had influenza that was refractory to antiviral treatment with this drug A neuraminidase I117M mutation that might influence oseltamivir susceptibility was detected in sequential specimens from 1 patient

引用

页码：1938 / 1942

页数：5

共 8 条

[1]

[Anonymous], 2009, Wkly Epidemiol Rec, V85, P37

[2] Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team [J].

Dawood, Fatimah S. ;

Jain, Seema ;

Finelli, Lyn ;

Shaw, Michael W. ;

Lindstrom, Stephen ;

Garten, Rebecca J. ;

Gubareva, Larisa V. ;

Xu, Xiyan ;

Bridges, Carolyn B. ;

Uyeki, Timothy M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (25) :2605-2615

[3] Susceptibility of Highly Pathogenic H5N1 Influenza Viruses to the Neuraminidase Inhibitor Oseltamivir Differs In Vitro and in a Mouse Model [J].

Govorkova, Elena A. ;

Ilyushina, Natalia A. ;

McClaren, Jennifer L. ;

Naipospos, Tri S. P. ;

Douangngeun, Bounlom ;

Webster, Robert G. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (07) :3088-3096

[4] Assessment of hemagglutinin sequence heterogeneity during influenza virus transmission in families [J].

Gubareva, LV ;

Novikov, DV ;

Hayden, FG .

JOURNAL OF INFECTIOUS DISEASES, 2002, 186 (11) :1575-1581

[5] Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes [J].

Hurt, A. C. ;

Selleck, P. ;

Komadina, N. ;

Shaw, R. ;

Brown, L. ;

Barr, I. G. .

ANTIVIRAL RESEARCH, 2007, 73 (03) :228-231

[6] The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design [J].

Russell, Rupert J. ;

Haire, Lesley F. ;

Stevens, David J. ;

Collins, Patrick J. ;

Lin, Yi Pu ;

Blackburn, G. Michael ;

Hay, Alan J. ;

Gamblin, Steven J. ;

Skehel, John J. .

NATURE, 2006, 443 (7107) :45-49

[7]

WHO, WEEKL UPD OS RES PAN

[8] Influenza sequence and epitope database [J].

Yang, Seok ;

Lee, Joo-Yeon ;

Lee, Joon Seung ;

Mitchell, Wayne P. ;

Oh, Hee-Bok ;

Kang, Chun ;

Kim, Kyung Hyun .

NUCLEIC ACIDS RESEARCH, 2009, 37 :D423-D430

← 1 →