Effectiveness of a nurse-led hospital-to-home transitional care intervention for older adults with multimorbidity and depressive symptoms: A pragmatic randomized controlled trial

被引:19
作者
Markle-Reid, Maureen [1 ]
McAiney, Carrie [2 ]
Fisher, Kathryn [1 ]
Ganann, Rebecca [1 ]
Gauthier, Alain P. [3 ]
Heald-Taylor, Gail [1 ]
McElhaney, Janet E. [4 ,5 ]
McMillan, Fran [6 ]
Petrie, Penelope [1 ]
Ploeg, Jenny [1 ]
Urajnik, Diana J. [6 ]
Whitmore, Carly [1 ]
机构
[1] McMaster Univ, Fac Hlth Sci, Sch Nursing, Aging Community & Hlth Res Unit, Hamilton, ON, Canada
[2] Univ Waterloo, Res Inst Aging, Sch Publ Hlth & Hlth Syst & Schlegel UW, Waterloo, ON, Canada
[3] Laurentian Univ, Sch Human Kinet, Sudbury, ON, Canada
[4] Northern Ontario Sch Med, Sudbury, ON, Canada
[5] Hlth Sci North Res Inst, Sudbury, ON, Canada
[6] Laurentian Univ, Ctr Rural & Northern Hlth Res, Sudbury, ON, Canada
关键词
GENERALIZED ANXIETY DISORDER; HEALTH-CARE; SELF-MANAGEMENT; READMISSIONS; DISCHARGE; QUESTIONNAIRE; INEQUALITIES; PREVALENCE; VALIDITY; SUPPORT;
D O I
10.1371/journal.pone.0254573
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objective To evaluate the effectiveness of a nurse-led hospital-to-home transitional care intervention versus usual care on mental functioning (primary outcome), physical functioning, depressive symptoms, anxiety, perceived social support, patient experience, and health service use costs in older adults with multimorbidity (>= 2 comorbidities) and depressive symptoms. Design and setting Pragmatic multi-site randomized controlled trial conducted in three communities in Ontario, Canada. Participants were allocated into two groups of intervention and usual care (control). Participants 127 older adults (>= 65 years) discharged from hospital to the community with multimorbidity and depressive symptoms. Intervention This evidence-based, patient-centred intervention consisted of individually tailored care delivery by a Registered Nurse comprising in-home visits, telephone follow-up and system navigation support over 6-months. Outcome measures The primary outcome was the change in mental functioning, from baseline to 6-months. Secondary outcomes were the change in physical functioning, depressive symptoms, anxiety, perceived social support, patient experience, and health service use cost, from baseline to 6-months. Intention-to-treat analysis was performed using ANCOVA modeling. Results Of 127 enrolled participants (63-intervention, 64-control), 85% had six or more chronic conditions. 28 participants were lost to follow-up, leaving 99 (47 -intervention, 52-control) participants for the complete case analysis. No significant group differences were seen for the baseline to six-month change in mental functioning or other secondary outcomes. Older adults in the intervention group reported receiving more information about health and social services (p = 0.03) compared with the usual care group. Conclusions Although no significant group differences were seen for the primary or secondary outcomes, the intervention resulted in improvements in one aspect of patient experience (information about health and social services). The study sample fell below the target sample (enrolled 127, targeted 216), which can account for the non-significant findings. Further research on the impact of the intervention and factors that contribute to the results is recommended.
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页数:25
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