Peptide quantitation using primary amine selective metal chelation labels for mass spectrometry

被引：11
作者：
Kerr, Thomas J.
McLean, John A. [1 ]
机构：
[1] Vanderbilt Univ, Dept Chem, Stevenson Ctr 7330, Nashville, TN 37235 USA
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 30期
关键词：
CODED AFFINITY TAGS; PROTEOMICS; PROTEINS; STABILITY; COMPLEXES; MS;
D O I：
10.1039/b926290c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Primary amine selective lanthanide metal chelating labels are demonstrated for enhancing the number of simultaneous relative peptide quantitation measurements that can be performed in mass spectrometry analyses.
引用
收藏
页码：5479 / 5481
页数：3
相关论文
共 14 条
  • [1] Mass spectrometry-based proteomics
    Aebersold, R
    Mann, M
    [J]. NATURE, 2003, 422 (6928) : 198 - 207
  • [2] A metal-coded affinity tag approach to quantitative proteomics
    Ahrends, Robert
    Pieper, Stefan
    Kuehn, Andreas
    Weisshoff, Hardy
    Hamester, Meike
    Lindemann, Torsten
    Scheler, Christian
    Lehmann, Karola
    Taubner, Kerstin
    Linscheid, Michael W.
    [J]. MOLECULAR & CELLULAR PROTEOMICS, 2007, 6 (11) : 1907 - 1916
  • [3] Strategies for increasing the sensitivity of gadolinium based MRI contrast agents
    Caravan, Peter
    [J]. CHEMICAL SOCIETY REVIEWS, 2006, 35 (06) : 512 - 523
  • [4] Quantitative profiling of proteins in complex mixtures using liquid chromatography and mass spectrometry
    Chelius, D
    Bondarenko, PV
    [J]. JOURNAL OF PROTEOME RESEARCH, 2002, 1 (04) : 317 - 323
  • [5] Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
    Gerber, SA
    Rush, J
    Stemman, O
    Kirschner, MW
    Gygi, SP
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (12) : 6940 - 6945
  • [6] Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    Gygi, SP
    Rist, B
    Gerber, SA
    Turecek, F
    Gelb, MH
    Aebersold, R
    [J]. NATURE BIOTECHNOLOGY, 1999, 17 (10) : 994 - 999
  • [7] Method for quantitative proteomics research by using metal element chelated tags coupled with mass spectrometry
    Liu, Huiling
    Zhang, Yangjun
    Wang, Jinglan
    Wang, Dong
    Zhou, Chunxi
    Cai, Yun
    Qian, Xiaohong
    [J]. ANALYTICAL CHEMISTRY, 2006, 78 (18) : 6614 - 6621
  • [8] Comparison of label-free methods for quantifying human proteins by shotgun proteomics
    Old, WM
    Meyer-Arendt, K
    Aveline-Wolf, L
    Pierce, KG
    Mendoza, A
    Sevinsky, JR
    Resing, KA
    Ahn, NG
    [J]. MOLECULAR & CELLULAR PROTEOMICS, 2005, 4 (10) : 1487 - 1502
  • [9] Thermal denaturation: A useful technique in peptide mass mapping
    Park, ZY
    Russell, DH
    [J]. ANALYTICAL CHEMISTRY, 2000, 72 (11) : 2667 - 2670
  • [10] Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS
    Steen, H
    Jebanathirajah, JA
    Springer, M
    Kirschner, MW
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (11) : 3948 - 3953
12