Polymeric iodophors with poly(2-ethyl-2-oxazoline) and poly (N-vinylpyrrolidone): optical, hydrodynamic, thermodynamic, and antimicrobial properties

被引:9
作者
Makhayeva, Danelya N. [1 ]
Filippov, Sergey K. [2 ,3 ]
Yestemes, Sanzhar S. [1 ]
Irmukhametova, Galiya S. [1 ]
Khutoryanskiy, Vitaliy V. [1 ,2 ]
机构
[1] Al Farabi Kazakh Natl Univ, Dept Chem & Chem Technol, Alma Ata 050040, Kazakhstan
[2] Univ Reading, Sch Pharm, Reading RG6 6DX, Berks, England
[3] Abo Akad Univ, Fac Sci & Engn, Pharmaceut Sci Lab, Turku 20520, Finland
关键词
Iodine; Iodophors; Polymers; Poly(N-vinylpyrrolidone); Poly(2-ethyl-2-oxazoline); Antimicrobial properties; POVIDONE-IODINE; THERMORESPONSIVE POLYMERS; POLYVINYLPYRROLIDONE; POLY(2-OXAZOLINE)S; NANOPARTICLES; PERMEABILITY; COMPLEXES; DIFFUSION; MICELLES; HALOGEN;
D O I
10.1016/j.eurpolymj.2022.111005
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Formation of iodophors by interactions of poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone) with molecular iodine dissolved in aqueous solutions with addition of potassium iodide and ethanol has been studied using a range of physicochemical techniques including UV-Vis spectroscopy, viscometry, dynamic light scattering, isothermal titration calorimetry and partitioning through semi-permeable membrane. It was established that poly(2-ethyl-2-oxazoline) exhibits greater ability to bind iodine compared to poly(N-vinylpyrrolidone). Despite the difference in the binding ability of these two polymers, their iodophors exhibited similar antimicrobial properties.
引用
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页数:10
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