Effect of cosolvents on the stabilization of bioactive peptides from bovine milk α-casein

被引：6

作者：

Srinivas, Sistla ^{[1
]}

Prakash, Vishweshwaraiah ^{[1
]}

机构：

[1] Cent Food Technol Res Inst, Dept Prot Chem & Technol, Mysore 570020, Karnataka, India

来源：

PROTEIN AND PEPTIDE LETTERS | 2008年 / 15卷 / 04期

关键词：

alpha-casein; cosolvents; polyols; peptides; stabilization; ACE activity; antioxidant activity;

D O I：

10.2174/092986608784246416

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Peptides with more than one biological activity are many a times multifunctional peptides. Two peptides with multifunctional properties from alpha(S2)-casein were stabilized in presence of cosolvents for their biological activities like ACE inhibition activity and antioxidant activity. These bioactive peptides in cosolvents were also thermostable. Infra red spectra of peptides in cosolvents reveal no change in the secondary structure in presence of cosolvents. Correlation between sequence, structure and composition of peptides on biological activities were studied.

引用

页码：371 / 376

页数：6

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